Evidence map›Paper›PMID 26651472›Full record

Trial reportHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2015

Pilot RCT of bidirectional text messaging for ART adherence among nonurban substance users with HIV.

Karen S Ingersoll, Rebecca A Dillingham, Jennifer E Hettema, Mark Conaway, Jason Freeman, George Reynolds, Sharzad Hosseinbor

2 registry-linked trialsAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 10 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01343654 nacompletednot on this map

RCT of a Text Messaging Adherence Assessment & Intervention Tool for Rural HIV+ Drug Users

TypeinterventionalSponsorUniversity of VirginiaRan2011 to 2013Enrolled54ConditionsHIV InfectionsArmsText messaging plus EMA, Treatment as usual
NCT04998019 nacompletednot on this mapstarted 2022, after this paper: background citation

Pragmatic Efficacy Trial of mHealth to Improve HIV Outcomes in the DC Cohort

TypeinterventionalSponsorGeorge Washington UniversityRan2022 to 2025Enrolled682ConditionsHIV/AIDSArmsPositiveLinks
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 10 syntheses or guidelines pooled it, 77 citations in OpenAlex.

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  12. Description of patient questions received by clinical pharmacists in the Nudge Study.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Karen S IngersollDepartment of Psychiatry and Neurobehavioral Sciences, University of Virginia School of Medicine.
Rebecca A DillinghamDepartment of Medicine, University of Virginia School of Medicine.
Jennifer E HettemaDepartment of Psychiatry and Neurobehavioral Sciences, University of Virginia School of Medicine.
Mark ConawayDepartment of Public Health Sciences, University of Virginia School of Medicine.
Jason FreemanDepartment of Psychiatry and Neurobehavioral Sciences, University of Virginia School of Medicine.
George ReynoldsHealth Decision Technologies.
Sharzad HosseinborDepartment of Psychiatry and Neurobehavioral Sciences, University of Virginia School of Medicine.
University of Virginia · USHealth Decision Technologies (United States) · US

Funding

Text Messaging Adherence Assessment & Intervention Tool for Rural HIV+ Drug UsersR34DA031640 · NIDA · UNIVERSITY OF VIRGINIA · PI INGERSOLL, KAREN S · 2011 to 2012
$693k
NIDA NIH HHS R34 DA031640
6 · The paper itself

Abstract

objectiveThis pilot study tested the preliminary efficacy of a theory-based bidirectional text messaging intervention (TEXT) on antiretroviral (ART) adherence, missed care visits, and substance use among people with HIV.

methodParticipants with recent substance use and ART nonadherence from 2 nonurban HIV clinics were randomized to TEXT or to usual care (UC). The TEXT intervention included daily queries of ART adherence, mood, and substance use. The system sent contingent intervention messages created by participants for reports of adherence/nonadherence, good mood/poor mood, and no substance use/use. Assessments were at preintervention, postintervention, and 3-month postintervention follow-up. Objective primary outcomes were adherence, measured by past 3-month pharmacy refill rate, and proportion of missed visits (PMV), measured by medical records. The rate of substance-using days from the timeline follow-back was a secondary outcome.

resultsSixty-three patients participated, with 33 randomized to TEXT and 30 to UC. At preintervention, adherence was 64.0%, PMV was 26.9%, and proportion of days using substances was 53.0%. At postintervention, adherence in the TEXT condition improved from 66% to 85%, compared with 62% to 71% in UC participants (p = .04). PMV improved from 23% to 9% for TEXT participants and 31% to 28% in UC participants (p = .12). There were no significant differences between conditions in substance-using days at postintervention. At 3-month follow-up, differences were not significant.

conclusionsPersonalized bidirectional text messaging improved adherence and shows promise to improve visit attendance, but did not reduce substance using days. This intervention merits further testing and may be cost-efficient given its automation.

Indexed as

Reminder SystemsText MessagingAdultAnti-HIV AgentsAppointments and SchedulesFemaleFollow-Up StudiesHIV InfectionsHumansMaleMedication AdherenceMiddle AgedPilot ProjectsSubstance-Related DisordersAnti-HIV Agents

Identifiers

PMID26651472
PMCPMC4681310
OpenAlexW2413251969

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.