Evidence map›Paper›PMID 26650935›Full record

ArticleEuropean radiology2016

Quantitative evaluation of beam-hardening artefact correction in dual-energy CT myocardial perfusion imaging.

Andreas M Bucher, Julian L Wichmann, U Joseph Schoepf, Christopher D Wolla, Christian Canstein, Andrew D McQuiston, Aleksander W Krazinski, Carlo N De Cecco, Felix G Meinel, Thomas J Vogl and 1 more

Abstract read
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In one paragraph

Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Dual-Energy CT of the Heart: A Review.Journal of imaging · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andreas M BucherDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA.
Julian L WichmannDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA.
U Joseph SchoepfDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA. schoepf@musc.edu.
Christopher D WollaDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA.
Christian CansteinCT Division, Siemens Medical Solutions, Malvern, PA, USA.
Andrew D McQuistonDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA.
Aleksander W KrazinskiDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA.
Carlo N De CeccoDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA.
Felix G MeinelDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA.
Thomas J VoglDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt, Germany.
Lucas L GeyerDivision of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Drive, Charleston, SC, 29401, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess quantitatively the impact of a novel reconstruction algorithm ("kernel") with beam-hardening correction (BHC) on beam-hardening artefacts of the myocardium at dual-energy CT myocardial perfusion imaging (DE-CTMPI).

methodsRest-series of DE-CTMPI examinations from 14 patients were retrospectively analyzed. Six image series were reconstructed for each patient: a) 100 kV, b) 140 kV, and c) linearly blended MIX0.5, each with BHC (D33f kernel) and without (D30f kernel). Seven hundred and fifty-six myocardial regions were assessed. Seven equal regions of interest divided the myocardium in the axial section. Three subdivisions were created within these regions in areas prone to BHA. Reports of SPECT studies performed within 30 days of CT examination were used to confirm the presence and location of true perfusion defects. Paired student t-test was used for statistical evaluation.

resultsOverall mean myocardial attenuation was lower using BHC (D30f: 87.3 ± 24.1 HU; D33f: 85.5 ± 21.5 HU; p = 0.009). Overall relative difference from average myocardial attenuation (RDMA) was more homogeneous using BHC (D30f: -0.3 ± 11.4 %; D33f: 0.1 ± 10.1 %; p < 0.001). Changes in RDMA were greatest in the posterobasal myocardium (D30f: -16.2 ± 10.0 %; D33f: 3.4 ± 10.7 %; p < 0.001).

conclusionsA dedicated reconstruction algorithm with BHC can significantly reduce beam-hardening artefacts in DE-CTMPI. KEY POINTS: • Beam-hardening artefacts (BHA) cause interference with attenuation-based CT myocardial perfusion assessment (CTMPI). • BHA occur mostly in the posterobasal left ventricular wall. • Beam-hardening correction homogenized and decreased mean myocardial attenuation. • BHC can help avoid false-positive findings and increase specificity of static CTMPI.

Indexed as

AgedAlgorithmsArtifactsFemaleHeartHumansMaleMiddle AgedRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedArtefactsCardiac imaging techniqueImage enhancementsImage reconstructionMyocardial perfusion imaging

Identifiers

PMID26650935

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.