Evidence map›Paper›PMID 26650848›Full record

ArticleeLife2015

Ion channels and calcium signaling in motile cilia.

Julia F Doerner, Markus Delling, David E Clapham

Open access · goldAbstract read
In one paragraph

Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Convergence of autism proteins at the cilium.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. TRPV4 Channel Modulators as Potential Drug Candidates for Cystic Fibrosis.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Article
  9. Islet cilia and glucose homeostasis.Frontiers in cell and developmental biology · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Activation of airway epithelial bitter taste receptors byThe Journal of biological chemistry · 2018
    Article
  14. A Parallel Modular Biomimetic Cilia Sorting Platform.Biomimetics (Basel, Switzerland) · 2018
    Article
  15. Article
  16. Article
  17. Routes and machinery of primary cilium biogenesis.Cellular and molecular life sciences : CMLS · 2017
    Review
  18. Progress in ciliary ion channel physiology.The Journal of general physiology · 2017
    Review
  19. Spatial and temporal specificity of CaThe New phytologist · 2016
    Article
  20. Voltage-gated calcium channels of Paramecium cilia.The Journal of experimental biology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Julia F DoernerDepartment of Cardiology, Howard Hughes Medical Institute, Boston Children's Hospital, Boston, United States.
Markus DellingDepartment of Cardiology, Howard Hughes Medical Institute, Boston Children's Hospital, Boston, United States.
David E ClaphamDepartment of Cardiology, Howard Hughes Medical Institute, Boston Children's Hospital, Boston, United States.
Boston Children's Hospital · USHoward Hughes Medical Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The beating of motile cilia generates fluid flow over epithelia in brain ventricles, airways, and Fallopian tubes. Here, we patch clamp single motile cilia of mammalian ependymal cells and examine their potential function as a calcium signaling compartment. Resting motile cilia calcium concentration ([Ca

Indexed as

biophysicscalciumcell biologyion channelsmotile ciliamousepatch clampstructural biology

Identifiers

PMID26650848
PMCPMC4714969
OpenAlexW2273212437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.