Evidence map›Paper›PMID 26650045›Full record

ArticleMolecular neurobiology2016

NMR-Based Metabolomics Reveal a Recovery from Metabolic Changes in the Striatum of 6-OHDA-Induced Rats Treated with Basic Fibroblast Growth Factor.

Hong Zheng, Liangcai Zhao, Huanhuan Xia, Cuicui Xu, Dan Wang, Kun Liu, Li Lin, Xiaokun Li, Zhihan Yan, Hongchang Gao

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hong ZhengSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Liangcai ZhaoSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Huanhuan XiaSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Cuicui XuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Dan WangSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Kun LiuRadiology Department of the Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Li LinSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Xiaokun LiSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Zhihan YanRadiology Department of the Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, 325027, China. zhihanyan@hotmail.com.
Hongchang GaoSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. gaohc27@wmu.edu.cn.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basic fibroblast growth factor (bFGF) has a potential role in the treatment of Parkinson's disease (PD) due to its neurotrophic effect on dopaminergic neurons. To address the metabolic mechanisms of bFGF administration on PD, we have analyzed the metabolic profiles in the striatum of 6-hydroxydopamine (6-OHDA)-induced PD rats after the treatment with bFGF using

Indexed as

Magnetic Resonance SpectroscopyMetabolomicsAnimalsCorpus StriatumDiscriminant AnalysisFibroblast Growth Factor 2Least-Squares AnalysisMaleNeuronsOxidopamineParkinson DiseaseRats, Sprague-DawleyTyrosine 3-MonooxygenaseFibroblast Growth Factor 2OxidopamineTyrosine 3-MonooxygenasebFGFGABAGlutamineMetabolomicsParkinson’s diseaseStriatum

Identifiers

PMID26650045
OpenAlexW2192090354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.