ArticleEuropean journal of epidemiology2015
The Rotterdam Scan Study: design update 2016 and main findings.
Article in European journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
106 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Technical and clinical validation of commercial automated volumetric MRI tools for dementia diagnosis-a systematic review.Neuroradiology · 2021Pooled it
- Translating research findings into clinical practice: a systematic and critical review of neuroimaging-based clinical tools for brain disorders.Translational psychiatry · 2020Pooled it
- Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2018Pooled it
- Cognition in Cardiovascular Disease.Current neurology and neuroscience reports · 2026Review
- The blood metabolome of brain health in midlife and influences of genes, microbiome and exposome.Nature aging · 2026Article
- Automated MRI-based brain volumetric analysis in women with polycystic ovary syndrome.BMC medical imaging · 2026Observational
- Imaging-genetics-based dementia risk prediction using deep survival neural networks in the Rotterdam Study.Scientific reports · 2026Article
- Brain Atrophy Associated With Risk Variant rs10191329 Extends Beyond Multiple Sclerosis.Annals of neurology · 2026Article
- Preeclampsia as a reversible risk factor for Alzheimer's disease: A prospective MRI study on morphological changes of the cerebral cortex and impairment of cognitive functions.The journal of prevention of Alzheimer's disease · 2026Article
- Loss of microstructural integrity in left hemispheric white matter tracts is associated with poorer digits in noise understanding.GeroScience · 2026Article
- Relation between Cerebral Small Vessel Function at 7T MRI and Small Vessel Disease Burden in a General Aging Population.Cerebrovascular diseases (Basel, Switzerland) · 2026Article
- Head-to-head comparison of diffusion imaging markers for cognitive decline and risk of dementia: The population-based Rotterdam Study.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Risk of Cardiovascular Disease With Co-Occurring Covert Brain Infarction and Unrecognized Myocardial Infarction.Journal of the American Heart Association · 2025Article
- Imaging-genetics-based dementia risk prediction using deep survival neural networks in the Rotterdam Study.Research square · 2025Article
- Objective physical activity and Alzheimer's disease burden in the population-based Rotterdam Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Subcortical gray matter volumes and 5-year dementia risk in individuals with subjective cognitive decline or mild cognitive impairment: A multi-cohort analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Multiple Sclerosis-Specific Reference Curves for Brain Volumes to Explain Disease Severity.Neurology · 2025Observational
- Pulmonary embolism prophylaxis and treatment: What's right, what's wrong, and the future.Chinese medical journal pulmonary and critical care medicine · 2025Review
- Effect of carotid artery stenosis on cortical microinfarcts, white matter integrity, and brain volume: An interhemispheric comparison within the population-based Rotterdam Study.Cerebral circulation - cognition and behavior · 2025Article
- Contributions of lifestyle, education, and cardiovascular risk factors to the brain age gap.Aging brain · 2025Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random subsamples of participants from the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. Moreover, we describe the imaging protocol, image post-processing techniques, and the main findings to date. Finally, we provide recommendations for future research, which will also be topics of investigation in the Rotterdam Scan Study.
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Registered trials
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