Evidence map›Paper›PMID 26649756›Full record

ReviewCurrent opinion in genetics & development2015

Genomics and the making of yeast biodiversity.

Chris Todd Hittinger, Antonis Rokas, Feng-Yan Bai, Teun Boekhout, Paula Gonçalves, Thomas W Jeffries, Jacek Kominek, Marc-André Lachance, Diego Libkind, Carlos A Rosa and 2 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
22.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 126 citations in OpenAlex.

  1. Article
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  5. Accurate, scalable, and fully automated inference of species trees from raw genome assemblies using ROADIES.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
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  9. Article
  10. Machine learning enables identification of an alternative yeast galactose utilization pathway.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
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  14. Promoters in Pichia pastoris: A Toolbox for Fine-Tuned Gene Expression.Methods in molecular biology (Clifton, N.J.) · 2024
    Review
  15. Article
  16. Mitochondrial Genome Diversity across the Subphylum Saccharomycotina.bioRxiv : the preprint server for biology · 2023
    Article
  17. Article
  18. Article
  19. Journal of fungi (Basel, Switzerland) · 2022
    Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 7 countries.

Chris Todd HittingerLaboratory of Genetics, Genome Center of Wisconsin, Wisconsin Energy Institute, J.F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53706, USA; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: cthittinger@wisc.edu.
Antonis RokasDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Feng-Yan BaiState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Teun BoekhoutState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands; Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Paula GonçalvesUCIBIO-REQUIMTE, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
Thomas W JeffriesDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Jacek KominekLaboratory of Genetics, Genome Center of Wisconsin, Wisconsin Energy Institute, J.F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53706, USA.
Marc-André LachanceDepartment of Biology, University of Western Ontario, London, ON N6A 5B7, Canada.
Diego LibkindLaboratorio de Microbiología Aplicada y Biotecnología, Instituto de Investigaciones en Biodiversidad y Medioambiente (INIBIOMA), UNComahue-CONICET, Bariloche, Argentina.
Carlos A RosaDepartment of Microbiology, ICB, Federal University of Minas Gerais, C.P. 486, Belo Horizonte, MG 31270-901, Brazil.
José Paulo SampaioUCIBIO-REQUIMTE, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
Cletus P KurtzmanBacterial Foodborne Pathogens and Mycology Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, US Department of Agriculture, Peoria, IL, USA.
University of Wisconsin–Madison · USAgricultural Research Service · USChinese Academy of Sciences · CNConsejo Nacional de Investigaciones Científicas y Técnicas · ARRede de Química e Tecnologia · PTUniversidade Federal de Minas Gerais · BRUniversidade Nova de Lisboa · PTVanderbilt University · USWesterdijk Fungal Biodiversity Institute · NLWestern University · CA

Funding

Midgut Transcriptome and Proteome Analyses: Non-model Anopheline Malaria VectorsR21AI105619 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DINGLASAN, RHOEL DAVID RAMOS · 2014 to 2015
$454k
NIAID NIH HHS AI105619NIAID NIH HHS R21 AI105619
6 · The paper itself

Abstract

Yeasts are unicellular fungi that do not form fruiting bodies. Although the yeast lifestyle has evolved multiple times, most known species belong to the subphylum Saccharomycotina (syn. Hemiascomycota, hereafter yeasts). This diverse group includes the premier eukaryotic model system, Saccharomyces cerevisiae; the common human commensal and opportunistic pathogen, Candida albicans; and over 1000 other known species (with more continuing to be discovered). Yeasts are found in every biome and continent and are more genetically diverse than angiosperms or chordates. Ease of culture, simple life cycles, and small genomes (∼10-20Mbp) have made yeasts exceptional models for molecular genetics, biotechnology, and evolutionary genomics. Here we discuss recent developments in understanding the genomic underpinnings of the making of yeast biodiversity, comparing and contrasting natural and human-associated evolutionary processes. Only a tiny fraction of yeast biodiversity and metabolic capabilities has been tapped by industry and science. Expanding the taxonomic breadth of deep genomic investigations will further illuminate how genome function evolves to encode their diverse metabolisms and ecologies.

Indexed as

BiodiversityGenomicsBase SequenceCandida albicansGenetic VariationGenome, FungalHigh-Throughput Nucleotide SequencingSaccharomyces cerevisiae

Identifiers

PMID26649756
PMCPMC4771062
OpenAlexW2195930427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.