ArticleNew microbes and new infections2015
Clostridium difficile infections among adults and children in Mwanza/Tanzania: is it an underappreciated pathogen among immunocompromised patients in sub-Saharan Africa?
Article in New microbes and new infections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antimicrobial resistance in Clostridioides (Clostridium) difficile derived from humans: a systematic review and meta-analysis.Antimicrobial resistance and infection control · 2020Pooled it
- Best Practices in the Management ofTropical medicine and infectious disease · 2024Review
- Make It LessGenes · 2022Review
- HighInternational journal of pediatrics · 2020Article
- High levels of toxigenicAccess microbiology · 2020Article
- High Prevalence of Multidrug-ResistantFrontiers in cellular and infection microbiology · 2020Article
- High rate of Clostridium difficile among young adults presenting with diarrhea at two hospitals in Kenya.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2018Article
- Prevalence and Strain Characterization ofFrontiers in microbiology · 2018Article
- Review
Corrections and comments
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Authors and funding
9 authors.
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Abstract
Little is known regarding the epidemiology Clostridium difficile in developing countries. Fresh stool samples from patients with diarrhoea were cultured anaerobically. C. difficile was detected in nine (6.4%) of 141 (95% confidence interval 4.2-13.1), of which seven (77.8%) were from children. HIV infection, prolonged hospitalization and antibiotic use were independent factors associated with the occurrence of C. difficile in the gastrointestinal tract. Two of the toxigenic isolates were typed as ribotype 045, and the other two had unknown ribotype. All C. difficile isolates were susceptible to metronidazole, moxifloxacin and clarithromycin, while three isolates were resistant to clarithromycin. C. difficile may be an important pathogen causing diarrhoea in sub-Saharan Africa among immunocompromised patients.
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