ArticlePakistan journal of medical sciences
Factor analysis of the biochemical markers related to liver cirrhosis.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Evaluating the Discriminative Performance of Noninvasive Biomarkers in Chronic Hepatitis B/C, Alcoholic Cirrhosis, and Nonalcoholic Cirrhosis: A Comparative Analysis.Diagnostics (Basel, Switzerland) · 2025Article
- Albumin‑bilirubin grade and INR for the prediction of esophagogastric variceal rebleeding after endoscopic treatment in cirrhosis.Experimental and therapeutic medicine · 2023Article
- INR-to-platelet ratio (INPR) as a novel noninvasive index for predicting liver fibrosis in chronic hepatitis B.International journal of medical sciences · 2021Observational
- Gamma-glutamyl transpeptidase to platelet ratio index is a good noninvasive biomarker for predicting liver fibrosis in Chinese chronic hepatitis B patients.The Journal of international medical research · 2016Observational
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3 authors.
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Abstract
objectivesThe purpose of this study was to find the correlations between biochemical study and liver cirrhosis.
methodsThe patients had liver biopsy to check the degree of their liver fibrosis, from August 2013 to August 2014 at the current medical center. In order to find the etiology of hepatitis, a research was done on gender, age, weight, and biochemical study through the investigation of subjects' medical record and medical history. For biochemical study, we examined hemoglobin, platelets, albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin, gamma-glutamyl transferase (GGT), prothrombin time (PT), and international normalised ratio (INR). We also analyzed the factors that are related to liver cirrhosis.
resultsAs a result, the patients at liver cirrhosis F≥2 stage showed 0.973, which is higher than the patients at FO stage with 0.943. F≥2 stage of hemoglobin was 0.544, which is lower than FO stage of hemoglobin with 0.817. Platelet count in F≥2 stage was 0.417, which is higher than FO stage with 0.074. For Albumin, F≥2 stage was 0.155 when F0 stage was 0.135. ATS's F≥2 stage was 0.665, which is 6 times higher than FO stage with 0.100. Moreover, in the case of GGT, F≥2 stage was higher with 0.492 than FO stage with 0.078.
conclusionsIn conclusion, it was confirmed that there is an increase in liver cirrhosis in the following general characteristics and biochemical factors: increase of age, increase of GGT, decrease of albumin, increase of the total bilirubin, and growth of INR (International Normalized Ratio).
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