Evidence map›Paper›PMID 26648627›Full record

ReviewAustralian prescriber2015

Prescribing azithromycin.

Brendan J McMullan, Mona Mostaghim

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Australian prescriber, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04699097 (Azitromycin Use in COVID-19 Positive Pediatric Patients; Effect on Ventricle Repolarization), which is not on this map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04699097 completednot on this mapstarted 2020, after this paper: background citation

Azitromycin Use in COVID-19 Positive Pediatric Patients; Effect on Ventricle Repolarization

TypeobservationalSponsorKayseri City HospitalRan2020 to 2020Enrolled105ConditionsAzithromycin Adverse Reaction, Covid19, Long QT SyndromeArmsAzithromycin
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 98 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
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  7. Gut Microbial Diversity in Antibiotic-Naive Children After Systemic Antibiotic Exposure: A Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Veterinary world · 2024
    Review
  13. Article
  14. Role of Cytochrome P450 2C9 in COVID-19 Treatment: Current Status and Future Directions.European journal of drug metabolism and pharmacokinetics · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Effects of azithromycin on ventricular repolarization in children with COVID-19.Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brendan J McMullanSydney Children's Hospital.
Mona MostaghimSydney Children's Hospital.
Sydney Children's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and excellent tissue penetration. It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used in preference to other macrolides for some sexually transmitted and enteric infections. Azithromycin has additional immunomodulatory effects and has been used in chronic respiratory inflammatory diseases for this purpose. Potential major adverse effects include cardiovascular arrhythmias and hearing loss. Macrolide resistance is also a problem, as are interactions with commonly prescribed drugs.

Indexed as

antibiotic resistanceazithromycinimmunomodulatorsmacrolide antibiotics

Identifiers

PMID26648627
PMCPMC4653965
OpenAlexW4230872349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.