ArticleNature communications2015
Conformational gating of DNA conductance.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Developing design guidelines for controlling charge transport in DNA.Nature chemistry · 2026Article
- From single step hops to emergent biological phenomena.Journal of inorganic biochemistry · 2026Review
- Transition from the Nanoscale to Bulk in the Nonequilibrium Optical Response of Laser-Dressed Materials.The journal of physical chemistry letters · 2026Article
- Decoding information stored in DNAs through single-molecule electrical detection platforms.Innovation (Cambridge (Mass.)) · 2025Review
- Recent Progress in DNA Biosensors: Target-Specific and Structure-Guided Signal Amplification.Biosensors · 2025Review
- Single-Molecule Electrical Conductance in Z-form DNA:RNA.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Biosensors for Public Health and Environmental Monitoring: The Case for Sustainable Biosensing.ACS sustainable chemistry & engineering · 2024Review
- Electronic Properties of DNA Origami Nanostructures Revealed byThe journal of physical chemistry. B · 2024Article
- Charge transport in individual short base stacked single-stranded RNA molecules.Scientific reports · 2023Article
- Electrical detection of RNA cancer biomarkers at the single-molecule level.Scientific reports · 2023Article
- Mapping DNA Conformations Using Single-Molecule Conductance Measurements.Biomolecules · 2023Article
- Recent Advances in Single-Molecule Sensors Based on STM Break Junction Measurements.Biosensors · 2022Review
- Single-molecule junction spontaneously restored by DNA zipper.Nature communications · 2021Article
- Article
- Backbone charge transport in double-stranded DNA.Nature nanotechnology · 2020Article
- Evolutionary advantage of anti-parallel strand orientation of duplex DNA.Scientific reports · 2020Article
- Detection and identification of genetic material via single-molecule conductance.Nature nanotechnology · 2018Article
- Direct observation of single-molecule hydrogen-bond dynamics with single-bond resolution.Nature communications · 2018Article
- Comparison of the Binding Geometry of Free-Base and Hexacoordinated Cationic Porphyrins to A- and B-Form DNA.ACS omega · 2018Article
- DNA-Based Single-Molecule Electronics: From Concept to Function.Journal of functional biomaterials · 2018Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA is a promising molecule for applications in molecular electronics because of its unique electronic and self-assembly properties. Here we report that the conductance of DNA duplexes increases by approximately one order of magnitude when its conformation is changed from the B-form to the A-form. This large conductance increase is fully reversible, and by controlling the chemical environment, the conductance can be repeatedly switched between the two values. The conductance of the two conformations displays weak length dependencies, as is expected for guanine-rich sequences, and can be fit with a coherence-corrected hopping model. These results are supported by ab initio electronic structure calculations that indicate that the highest occupied molecular orbital is more disperse in the A-form DNA case. These results demonstrate that DNA can behave as a promising molecular switch for molecular electronics applications and also provide additional insights into the huge dispersion of DNA conductance values found in the literature.
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Registered trials
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