ArticleEuropean journal of clinical nutrition2016
Intakes of folate, vitamin B6 and B12 and risk of depression in community-dwelling older adults: the Quebec Longitudinal Study on Nutrition and Aging.
Article in European journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.
- Evidence of the Importance of Dietary Habits Regarding Depressive Symptoms and Depression.International journal of environmental research and public health · 2020Pooled it
- Prevention of depression through nutritional strategies in high-risk persons: rationale and design of the MooDFOOD prevention trial.BMC psychiatry · 2016Trial
- Dietary habits, dietary diversity, and the influence of work-related stress among male academic professionals in Ibadan, Nigeria: a cross-sectional study.Journal of health, population, and nutrition · 2026Article
- Pathogenesis of HIV-associated depression: contributing factors and underlying mechanisms.Frontiers in psychiatry · 2025Review
- Nutritional Modulation of the Gut-Brain Axis: A Comprehensive Review of Dietary Interventions in Depression and Anxiety Management.Metabolites · 2024Review
- Exploring the Association between Serum B Vitamins, Homocysteine and Mental Disorders: Insights from Mendelian Randomization.Nutrients · 2024Article
- How Do Anger and Impulsivity Impact Fast-Food Consumption in Transitional Age Youth?AJPM focus · 2024Article
- Associations of dietary methyl donor nutrients with common psychological conditions (depression, anxiety and stress) among reproductive-aged women in Kabul, Afghanistan.BMC nutrition · 2023Article
- Key Nutrients for Optimal Blood Glucose Control and Mental Health in Individuals with Diabetes: A Review of the Evidence.Nutrients · 2023Review
- Article
- Gut-brain axis: altered microbiome and depression - review.Annals of medicine and surgery (2012) · 2023Article
- Gut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Egg consumption reduces the risk of depressive symptoms in the elderly: findings from a 6-year cohort study.BMC psychiatry · 2023Article
- Dietary Intake of Micronutrients and Essential Fatty Acids among Overweight or Obese Pregnant Women during Early Pregnancy.Journal of pediatrics, perinatology and child health · 2023Article
- A personalized diet intervention improves depression symptoms and changes microbiota and metabolite profiles among community-dwelling older adults.Frontiers in nutrition · 2023Article
- Biological Role of Nutrients, Food and Dietary Patterns in the Prevention and Clinical Management of Major Depressive Disorder.Nutrients · 2022Review
- B Vitamins, work-related stress and emotional mental disorders: a cross-sectional study among nurses in Indonesia.Nursing open · 2022Article
- Nutrition, Epigenetics, and Major Depressive Disorder: Understanding the Connection.Frontiers in nutrition · 2022Review
- Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.Public health nutrition · 2021Article
- Analysis of the Effects of Nutrient Intake and Dietary Habits on Depression in Korean Adults.Nutrients · 2021Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
BACKGROUND/
objectivesDepression can decrease quality of life and affect health outcomes in older population. We investigated whether different intake levels of folate, vitamin B6 and B12 were associated with a 3-year depression incidence among generally healthy, community-dwelling older men and women. SUBJECTS/
methodsParticipants in the Québec Longitudinal Study on Nutrition and Aging (NuAge), free of depression (that is, 30-item Geriatric Depression Scale (GDS) <11) at baseline (N=1368; 74 ± 4 years old; 50.5% women), were screened annually for incident depression (GDS ⩾ 11) or antidepressant medication. Tertiles of intakes (food only and food+supplements) were obtained from the mean of three non-consecutive 24-h recalls at baseline. Sex-stratified multiple logistic regression models were adjusted for age, physical activity, physical functioning, stressful life events and total energy intake.
resultsOver 3 years, 170 participants were identified as depressed. Women in the highest tertile of B6 intake from food were 43% less likely to become depressed when adjusting for demographic and health factors (multivariate odds ratio (OR) 0.57, 95% confidence interval (CI) 0.39-0.96), but adjustment for energy intake attenuated the effect. Men in the highest tertile of dietary B12 intake had decreased risk of depression (energy-adjusted multivariate OR 0.42, 95% CI 0.20-0.90). No other association was observed.
conclusionsThis study provides some evidence of decreased depression risk among women with higher intakes of vitamin B6 from food, which was dependent on total energy intake, and among men with higher intakes of B12 from food, independently of energy intake.
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