ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2016
Altered White Matter Microstructure in Adolescents and Adults with Bulimia Nervosa.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Altered thalamo–cortical and occipital–parietal– temporal–frontal white matter connections in patients with anorexia and bulimia nervosa: a systematic review of diffusion tensor imaging studiesJournal of psychiatry & neuroscience : JPN · 2019Pooled it
- Nonlinear associations between body mass index and brain microstructure across adolescence in the ABCD Study.bioRxiv : the preprint server for biology · 2026Article
- Annual Research Review: Neural mechanisms of eating disorders in youth - from current theory and findings to future directions.Journal of child psychology and psychiatry, and allied disciplines · 2026Review
- Alterations in the functional MRI-based temporal brain organisation in individuals with obesity.Diabetes, obesity & metabolism · 2025Article
- Causal relationship between bulimia nervosa and microstructural white matter: evidence from Mendelian randomization.Eating and weight disorders : EWD · 2025Article
- Support vector machine-based classification of bulimia nervosa using diffusion tensor imaging.Frontiers in psychiatry · 2025Article
- Exploring the neurobiological correlates of psilocybin-assisted psychotherapy in eating disorders: a review of potential methodologies and implications for the psychedelic study design.Journal of eating disorders · 2024Review
- Prefrontal-Limbic Circuitry Is Associated With Reward Sensitivity in Nonhuman Primates.Biological psychiatry · 2024Article
- Appearance-related cyberbullying and its association with the desire to alter physical appearance among adolescent females.Journal of eating disorders · 2024Article
- Alterations of interhemispheric functional homotopic connectivity and corpus callosum microstructure in bulimia nervosa.Quantitative imaging in medicine and surgery · 2023Article
- Aberrant impulse control circuitry in obesity.Molecular psychiatry · 2022Article
- Genetics and neurobiology of eating disorders.Nature neuroscience · 2022Review
- The effect of the demyelinating agent cuprizone on binge-like eating of sweetened palatable food in female and male C57BL/6 substrains.Appetite · 2020Article
- Disturbed Resting-State Whole-Brain Functional Connectivity of Striatal Subregions in Bulimia Nervosa.The international journal of neuropsychopharmacology · 2020Article
- The Neurobiology of Eating Disorders.Child and adolescent psychiatric clinics of North America · 2019Review
- Abnormal structural brain network and hemisphere-specific changes in bulimia nervosa.Translational psychiatry · 2019Article
- Attentional control abnormalities in posttraumatic stress disorder: Functional, behavioral, and structural correlates.Journal of affective disorders · 2019Article
- Altered cortical thickness and attentional deficits in adolescent girls and women with bulimia nervosa.Journal of psychiatry & neuroscience : JPN · 2018Article
- Abnormal fronto-striatal activation as a marker of threshold and subthreshold Bulimia Nervosa.Human brain mapping · 2018Article
- Altered intrinsic functional brain architecture in female patients with bulimia nervosa.Journal of psychiatry & neuroscience : JPN · 2017Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Previous data suggest structural and functional deficits in frontal control circuits in adolescents and adults with bulimia nervosa (BN), but less is known about the microstructure of white matter in these circuits early in the course of the disorder. Diffusion tensor imaging (DTI) data were acquired from 28 female adolescents and adults with BN and 28 age- and BMI-matched healthy female participants. Tract-based spatial statistics (TBSS) was used to detect group differences in white matter microstructure and explore the differential effects of age on white matter microstructure across groups. Significant reductions in fractional anisotropy (FA) were detected in the BN compared with healthy control group in multiple tracts including forceps minor and major, superior longitudinal, inferior fronto-occipital, and uncinate fasciculi, anterior thalamic radiation, cingulum, and corticospinal tract. FA reductions in forceps and frontotemporal tracts correlated inversely with symptom severity and Stroop interference in the BN group. These findings suggest that white matter microstructure is abnormal in BN in tracts extending through frontal and temporoparietal cortices, especially in those with the most severe symptoms. Age-related differences in both FA and RD in these tracts in BN compared with healthy individuals may represent an abnormal trajectory of white matter development that contributes to the persistence of functional impairments in self-regulation in BN.
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