ReviewJournal of dental research2016
Predicting Dental Caries Outcomes in Children: A "Risky" Concept.
Review in Journal of dental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association Between Iron Deficiency Anemia and Dental Caries in Children: A Systematic Umbrella Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Pooled it
- A systematic review of risk assessment tools for early childhood caries: is there evidence?European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020Pooled it
- Who Gets Dental Caries? A Comprehensive Review.Dentistry journal · 2026Review
- Evaluation of a Caregiver-Completed Questionnaire for Assessing Early Childhood Caries Risk: A Cross-Sectional Study.Cureus · 2026Article
- Epigenetic Age Acceleration, Neurocognition and Oral Health in Nigerian Adolescents With and Without HIV.The Pediatric infectious disease journal · 2026Article
- Equity or Two-Tier Care? Guardrails for Silver Diamine Fluoride and Delegated Early Childhood Caries Pathways.Children (Basel, Switzerland) · 2026Article
- Pilot validation of the new Canadian Caries Risk Assessment Tool for preschoolers.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2026Article
- Conceptualizing the Child's Right to Oral Health: A Rights-Based Approach to Dental Caries.Health and human rights · 2025Article
- Creating a Standardized Tool for Assessing Oral Health Awareness: A Psychometric Approach.Journal of pharmacy & bioallied sciences · 2025Article
- Multiancestry Genome-Wide Association Study of Early Childhood Caries.Journal of dental research · 2025Article
- A Narrative Review on Advancing Pediatric Oral Health: Comprehensive Strategies for the Prevention and Management of Dental Challenges in Children.Children (Basel, Switzerland) · 2025Review
- Assessment of overall caries risk and mode of birth delivery in infants and children with and without ECC: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- The Evolving Microbiome of Dental Caries.Microorganisms · 2024Review
- The prevalence of dental caries and its associated factors among preschool children in Huizhou, China: a cross-sectional study.Frontiers in oral health · 2024Article
- Subtypes of early childhood caries predict future caries experience.Community dentistry and oral epidemiology · 2023Article
- Behavioral and social determinants of early childhood caries among Palestinian preschoolers in Jerusalem area: a cross-sectional study.BMC oral health · 2023Article
- Salivary microbiome and metabolome analysis of severe early childhood caries.BMC oral health · 2023Article
- Guardians' Self-Reported Fair/Poor Oral Health Is Associated with Their Young Children's Fair/Poor Oral Health and Clinically Determined Dental Caries Experience.International journal of environmental research and public health · 2022Article
- Randomized clinical trial to evaluate two methods of caries risk assessment in schoolchildren: the CARDEC-PEL 04 study protocol.BMC oral health · 2021Article
- A Web-Based Rendering Application for Communicating Dental Conditions.Healthcare (Basel, Switzerland) · 2021Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
In recent years, unprecedented gains in the understanding of the biology and mechanisms underlying human health and disease have been made. In the domain of oral health, although much remains to be learned, the complex interactions between different systems in play have begun to unravel: host genome, oral microbiome with its transcriptome, proteome and metabolome, and more distal influences, including relevant behaviors and environmental exposures. A reasonable expectation is that this emerging body of knowledge can help improve the oral health and optimize care for individuals and populations. These goals are articulated by the National Institutes of Health as "precision medicine" and the elimination of health disparities. Key processes in these efforts are the discovery of causal factors or mechanistic pathways and the identification of individuals or population segments that are most likely to develop (any or severe forms of) oral disease. This article critically reviews the fundamental concepts of risk assessment and outcome prediction, as they relate to early childhood caries (ECC)-a common complex disease with significant negative impacts on children, their families, and the health system. The article highlights recent work and advances in methods available to estimate caries risk and derive person-level caries propensities. It further discusses the reasons for their limited utility in predicting individual ECC outcomes and informing clinical decision making. Critical issues identified include the misconception of defining dental caries as a tooth or surface-level condition versus a person-level disease; the fallacy of applying population-level parameters to individuals, termed privatization of risk; and the inadequacy of using frequentist versus Bayesian modeling approaches to derive individual disease propensity estimates. The article concludes with the notion that accurate caries risk assessment at the population level and "precision dentistry" at the person level are both desirable and achievable but must be based on high-quality longitudinal data and rigorous methodology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.