Evidence map›Paper›PMID 26647382›Full record

ArticleThe international journal of neuropsychopharmacology2016

Serotonin 5-HT7 Receptor in the Ventral Hippocampus Modulates the Retrieval of Fear Memory and Stress-Induced Defecation.

Yu Ohmura, Takayuki Yoshida, Kohtarou Konno, Masabumi Minami, Masahiko Watanabe, Mitsuhiro Yoshioka

Open access · goldAbstract read
In one paragraph

Article in The international journal of neuropsychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Serotonin 5-HTTranslational psychiatry · 2022
    Article
  6. Cognitive Deficit in Schizophrenia: From Etiology to Novel Treatments.International journal of molecular sciences · 2021
    Review
  7. Serotonin in the rat prefrontal cortex controls the micturition reflex through 5-hydroxytryptamine 2A and 5-hydroxytryptamine 7 receptors.International journal of urology : official journal of the Japanese Urological Association · 2020
    Article
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu OhmuraDepartment of Neuropharmacology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo, Japan (Dr Ohmura, Yoshida, and Yoshioka); Department of Anatomy, and (Drs Konno and Watanabe); Department of Pharmacology (Dr Minami), Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Japan. gwd0701@yahoo.co.jp.
Takayuki YoshidaDepartment of Neuropharmacology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo, Japan (Dr Ohmura, Yoshida, and Yoshioka); Department of Anatomy, and (Drs Konno and Watanabe); Department of Pharmacology (Dr Minami), Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Japan.
Kohtarou KonnoDepartment of Neuropharmacology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo, Japan (Dr Ohmura, Yoshida, and Yoshioka); Department of Anatomy, and (Drs Konno and Watanabe); Department of Pharmacology (Dr Minami), Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Japan.
Masabumi MinamiDepartment of Neuropharmacology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo, Japan (Dr Ohmura, Yoshida, and Yoshioka); Department of Anatomy, and (Drs Konno and Watanabe); Department of Pharmacology (Dr Minami), Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Japan.
Masahiko WatanabeDepartment of Neuropharmacology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo, Japan (Dr Ohmura, Yoshida, and Yoshioka); Department of Anatomy, and (Drs Konno and Watanabe); Department of Pharmacology (Dr Minami), Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Japan.
Mitsuhiro YoshiokaDepartment of Neuropharmacology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo, Japan (Dr Ohmura, Yoshida, and Yoshioka); Department of Anatomy, and (Drs Konno and Watanabe); Department of Pharmacology (Dr Minami), Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Japan.
Hokkaido University · JPSakurabashi Watanabe Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with posttraumatic stress disorder or panic disorder are often troubled by inappropriate retrieval of fear memory. Moreover, these disorders are often comorbid with irritable bowel syndrome. The main aim of the present study is to elucidate the involvement of hippocampal serotonergic systems in fear memory retrieval and stress-induced defecation. METHODS AND

resultsMicroinjection of serotonin

conclusionsThese results indicated that the released serotonin activates the serotonin

Indexed as

conditioned feardefecationhippocampusserotonergic

Identifiers

PMID26647382
PMCPMC4926794
OpenAlexW2295523987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.