ArticleBMC veterinary research2015
Seasonal variation in haematological and biochemical variables in free-ranging subadult brown bears (Ursus arctos) in Sweden.
Article in BMC veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Emergence from torpor rapidly elevates suppressed blood immune parameters in a bat species hibernating in a moderate climate.The Journal of experimental biology · 2026Article
- Transcriptome Remodeling and Adaptive Preservation of Muscle Protein Content in Hibernating Black Bears.Ecology and evolution · 2025Article
- Transcriptome remodeling and adaptive preservation of muscle protein content in hibernating black bears.bioRxiv : the preprint server for biology · 2025Article
- Convergent gut microbial functional strategies drive energy metabolism adaptation across Ursidae species and challenge the uniqueness of giant panda.The ISME journal · 2025Article
- Giant panda seasonal adaptations in feeding strategies and blood physiology.Frontiers in veterinary science · 2025Article
- Involvement of Melatonin, Oxidative Stress, and Inflammation in the Protective Mechanism of the Carotid Artery over the Torpor-Arousal Cycle of Ground Squirrels.International journal of molecular sciences · 2024Article
- Analysis of Lipid Metabolism in Adipose Tissue and Liver of Chinese Soft-Shelled TurtleInternational journal of molecular sciences · 2024Article
- Hematological and plasma profiles and ticks and tick-borne pathogens in wild Formosan black bears (Ursus thibetanus formosanus).Parasites & vectors · 2024Article
- Hematological and biochemical parameters of giant pandas (Conservation physiology · 2024Article
- Differential bone remodeling mechanism in hindlimb unloaded and hibernating Daurian ground squirrels: a comparison between artificial and natural disuse within the same species.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2023Article
- The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear (Animal welfare (South Mimms, England) · 2023Article
- Remarkable Plasticity of Bone Iron Homeostasis in Hibernating Daurian Ground Squirrels (International journal of molecular sciences · 2022Article
- Longitudinal study of northern fur seal (Callorhinus ursinus) hematology.The Journal of veterinary medical science · 2021Article
- Transcriptional changes and preservation of bone mass in hibernating black bears.Scientific reports · 2021Article
- Body Protein Sparing in Hibernators: A Source for Biomedical Innovation.Frontiers in physiology · 2021Review
- Specific shifts in the endocannabinoid system in hibernating brown bears.Frontiers in zoology · 2020Article
- Denning in brown bears.Ecology and evolution · 2020Review
- NON-INVASIVE BLOOD PRESSURE AND OTHER PHYSIOLOGICAL DATA IN CHEMICALLY IMMOBILIZED BROWN BEARS (Data in brief · 2020Article
- Comparison of two non-invasive arterial blood pressure monitoring techniques in brown bears (Veterinary and animal science · 2020Article
- Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.Frontiers in physiology · 2019Article
Corrections and comments
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFree-ranging brown bears exhibit highly contrasting physiological states throughout the year. They hibernate 6 months of the year, experiencing a decrease in body temperature, heart rate, respiratory rate and metabolism. An increase in food consumption and the resulting weight gain (mostly through fat storage) prior to hibernation are also part of the brown bear's annual cycle. Due to these physiological changes, haematological and biochemical variables vary dramatically throughout the year. Seasonal changes in 12 haematological and 34 biochemical variables were evaluated in blood samples collected from 40 free-ranging subadult brown bears (22 females, 18 males) immobilised in Sweden in winter (February-March), spring (April-May), and summer (June).
resultsHigher levels of haemoglobin, haematocrit and red blood cell count, and a lower white blood cell count and mean cell volume was found during hibernation than in spring and summer. Lower values of the enzymes; aspartate aminotransferase (AST), alanine transaminase (ALT), alkaline phosphatase (AP), γ-glutamyl transpeptidase (GGT), glutamate dehydrogenase (GD) and amylase, and increased values of β-hydroxybutyrate (β-HBA) and blood lipids; triglycerides, cholesterol and free fatty acids, were present during hibernation compared to spring and summer.
conclusionsThis study documents significant shifts in haematological and biochemical variables in samples collected from brown bears anaesthetised in winter (February-March) compared to in spring and summer (April-June), reflecting the lowered metabolic, renal and hepatic activity during hibernation. Lower values of enzymes and higher values of blood lipids during hibernation, likely reflect a lipid-based metabolism.
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