Evidence map›Paper›PMID 26646419›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2016

Poisonings Associated with Intubation: US National Poison Data System Exposures 2000-2013.

G A Beauchamp, S L Giffin, B Z Horowitz, A L Laurie, R Fu, R G Hendrickson

Abstract read
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In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Endotracheal Intubation in the Pharmaceutical-Poisoned Patient: a Narrative Review of the Literature.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

G A BeauchampOregon, Alaska and Guam Poison Center, Portland, OR, USA. beauchamp.gillian@gmail.com.
S L GiffinOregon, Alaska and Guam Poison Center, Portland, OR, USA.
B Z HorowitzOregon, Alaska and Guam Poison Center, Portland, OR, USA.
A L LaurieDepartment of Emergency Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
R FuSchool of Public Health, Oregon Health and Science University, Portland, OR, USA.
R G HendricksonOregon, Alaska and Guam Poison Center, Portland, OR, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients may be intubated after exposure to a variety of substances because of respiratory failure, CNS sedation, pulmonary pathology, or cardiovascular instability. However, there is little data describing the types of substances that are associated with endotracheal intubation or the rates of intubation after these exposures. Evaluation of this association may inform future research on intubation after exposures to specific substances and guide poison prevention education. Our objective was to determine which exposures were commonly associated with intubation using the data from National Poison Data System (NPDS). The NPDS tracks data from potential exposures to substances reported to all American Association of Poison Control Centers. We performed a retrospective analysis of NPDS data from January 1st, 2000 to December 31st, 2013 to identify human exposures to substances that were associated with endotracheal intubation. Descriptive statistics were used to analyze the data. There were 93,474 single substance exposures and 228,507 multiple substance exposures that were associated with intubation. The most common exposures to substances that were associated with intubation were atypical antipsychotics (7.4 %) for single exposures and benzodiazepines (27.4 %) for multiple exposures. Within each age group, the most common known exposures to substances were for patients under 6 years, clonidine for single and multiple exposures; for patients aged 6-12 years, clonidine for single exposures and atypical antipsychotics for multiple exposures; for patients aged 13-19 years, atypical antipsychotics for single and multiple exposures; and for patients over 19 years, atypical antipsychotics for single exposures and benzodiazepines for multiple exposures. From 2000-2013, the exposures to substances most commonly associated with intubation varied by single versus multiple exposures and by age. This study helps clarify the exposures to substances that are associated with intubation reported to poison centers in the USA.

Indexed as

Intubation, IntratrachealPractice Patterns, Physicians'AdolescentAdrenergic alpha-2 Receptor AgonistsAdultAge FactorsAnticonvulsantsAntidepressive Agents, TricyclicChildCombined Modality TherapyDrug OverdoseFemaleFuel OilsHealth Information ExchangeHumansInfantAdrenergic alpha-2 Receptor AgonistsAnticonvulsantsAntidepressive Agents, TricyclicFuel OilsEndotracheal intubationNational poison data systemPoisoningToxicologic exposure

Identifiers

PMID26646419
PMCPMC4880607

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.