Evidence map›Paper›PMID 26646292›Full record

ArticleAmerican journal of epidemiology2016

Age- and Sex-Specific Social Contact Patterns and Incidence of Mycobacterium tuberculosis Infection.

Peter J Dodd, Clare Looker, Ian D Plumb, Virginia Bond, Ab Schaap, Kwame Shanaube, Monde Muyoyeta, Emilia Vynnycky, Peter Godfrey-Faussett, Elizabeth L Corbett and 3 more

Abstract read
In one paragraph

Article in American journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Pooled it
  5. Pooled it
  6. Community-Wide Universal HIV Test and Treat Intervention Reduces Tuberculosis Transmission in Rural Uganda: A Cluster-Randomized Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
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  11. Cost-effectiveness of community tuberculosis screening in South Africa.American journal of respiratory and critical care medicine · 2026
    Article
  12. Article
  13. A global analysis of patterns of tuberculosis exposure and transmission.Proceedings of the National Academy of Sciences of the United States of America · 2026
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67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Peter J Dodd
Clare Looker
Ian D Plumb
Virginia Bond
Ab Schaap
Kwame Shanaube
Monde Muyoyeta
Emilia Vynnycky
Peter Godfrey-Faussett
Elizabeth L Corbett
Nulda Beyers
Helen Ayles
Richard G White

Funding

Medical Research Council G0802414Medical Research Council MR/J005088/1Wellcome Trust 091769Wellcome Trust GR095878
6 · The paper itself

Abstract

We aimed to model the incidence of infection with Mycobacterium tuberculosis among adults using data on infection incidence in children, disease prevalence in adults, and social contact patterns. We conducted a cross-sectional face-to-face survey of adults in 2011, enumerating "close" (shared conversation) and "casual" (shared indoor space) social contacts in 16 Zambian communities and 8 South African communities. We modeled the incidence of M. tuberculosis infection in all age groups using these contact patterns, as well as the observed incidence of M. tuberculosis infection in children and the prevalence of tuberculosis disease in adults. A total of 3,528 adults participated in the study. The reported rates of close and casual contact were 4.9 per adult per day (95% confidence interval: 4.6, 5.2) and 10.4 per adult per day (95% confidence interval: 9.3, 11.6), respectively. Rates of close contact were higher for adults in larger households and rural areas. There was preferential mixing of close contacts within age groups and within sexes. The estimated incidence of M. tuberculosis infection in adults was 1.5-6 times higher (2.5%-10% per year) than that in children. More than 50% of infections in men, women, and children were estimated to be due to contact with adult men. We conclude that estimates of infection incidence based on surveys in children might underestimate incidence in adults. Most infections may be due to contact with adult men. Treatment and control of tuberculosis in men is critical to protecting men, women, and children from tuberculosis.

Indexed as

Social BehaviorAdolescentAdultAge DistributionChildChild, PreschoolContact TracingCross-Sectional StudiesFamily CharacteristicsFemaleHumansIncidenceMaleMiddle AgedModels, TheoreticalMycobacterium tuberculosisdisease burdeninfection incidencesocial contact patterntuberculosis

Identifiers

PMID26646292
PMCPMC4706676

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.