Evidence map›Paper›PMID 26646243›Full record

ReviewJournal of molecular neuroscience : MN2016

The Role of Neuropeptides in Mouse Models of Colitis.

David Padua, John P Vu, Patrizia M Germano, Joseph R Pisegna

Open access · greenAbstract readReview
In one paragraph

Review in Journal of molecular neuroscience : MN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  18. Early Neurobehavioral Development of Mice Lacking Endogenous PACAP.Journal of molecular neuroscience : MN · 2017
    Article
  19. [Expression of vasoactive intestinal peptide in peripheral blood of children with hand, foot and mouth disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

David PaduaDivision of Digestive Diseases, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA.
John P VuDivision of Digestive Diseases, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA.
Patrizia M GermanoDivisions of Pulmonary and Critical Care, Department of Veterans Affairs, VA Greater Los Angeles Healthcare System, Los Angeles, CA, 90073, USA.
Joseph R PisegnaDivision of Gastroenterology, Hepatology and Parenteral Nutrition, Department of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA. jpisegna@ucla.edu.
University of California, Los Angeles · USVA Greater Los Angeles Healthcare System · US

Funding

Pilot and Feasibility ProgramP30DK041301 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROZENGURT, JUAN ENRIQUE · 1990 to 2019
$18.0M
GASTROENTEROLOGYT32DK007180 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JENSEN, DENNIS MICHAEL · 1986 to 2025
$10.0M
Gastrointestinal Hormonal Regulation of ObesityI01RX000194 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI PISEGNA, JOSEPH R, TACHE, YVETTE FRANCE · 2012 to 2015
–
Regulation of Appetite and Obesity by PACAPI01RX000873 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI GERMANO, PATRICIA MARIA · 2015 to 2015
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Intramural VA VA999999NIDDK NIH HHS P30 DK041301NIDDK NIH HHS T32 DK007180RRD VA I01 RX000194RRD VA I01 RX000873
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) constitutes an important clinically significant condition that results in morbidity and mortality. IBD can be generally classified into either ulcerative colitis (UC) or Crohn's disease (CD) that differs in the clinical and histopathology. The role of neuropeptides in the pathogenesis of these conditions is becoming increasingly recognized for their importance in modulating the inflammatory state. Animal models provide the greatest insight to better understand the pathophysiology of both disorders which will hopefully allow for improved treatment strategies. This review will provide a better understanding of the role of murine models for studying colitis.

Indexed as

AnimalsColitis, UlcerativeDextran SulfateDisease Models, AnimalGene DeletionIntestinal MucosaMiceNeuropeptidesTrinitrobenzenesulfonic AcidDextran SulfateNeuropeptidesTrinitrobenzenesulfonic AcidGastric acid secretionGastrinGastrointestinal hormonesPituitary adenylate cyclase-activating polypeptide (PACAP)Vasoactive intestinal polypeptide (VIP)

Identifiers

PMID26646243
PMCPMC4884658
OpenAlexW2270850078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.