ArticleObstetrics and gynecology2016
U.S. Food and Drug Administration's Guidance Regarding Morcellation of Leiomyomas: Well-Intentioned, But Is It Harmful for Women?
Article in Obstetrics and gynecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 56 citations in OpenAlex.
- From Presumed Leiomyoma to Stump: Laparoendoscopic Single-Site Hysterectomy with Contained Morcellation for a Large Unsuspected Borderline Smooth Muscle Tumor.Diagnostics (Basel, Switzerland) · 2026Article
- Exploring Surgical Strategies for Uterine Fibroid Treatment: A Comprehensive Review of Literature on Open and Minimally Invasive Approaches.Medicina (Kaunas, Lithuania) · 2023Review
- Development of an Algorithm to Differentiate Uterine Sarcoma from Fibroids Using MRI and LDH Levels.Diagnostics (Basel, Switzerland) · 2023Article
- Factors influencing surgical outcomes of laparoscopic myomectomy. A propensity-score matched analysis.Przeglad menopauzalny = Menopause review · 2022Article
- Conservative Management of Uterine Fibroid-Related Heavy Menstrual Bleeding and Infertility: Time for a Deeper Mechanistic Understanding and an Individualized Approach.Journal of clinical medicine · 2021Review
- Implementation of Total Laparoscopic Hysterectomy As the Default Technique and Lessons Learnt.Cureus · 2021Article
- Uterine smooth muscle tumour of uncertain malignant potential and in vitro fertilization treatment in an infertile patient.SAGE open medical case reports · 2021Article
- Investigating the diagnostic value of quantitative parameters based on T2-weighted and contrast-enhanced MRI with psoas muscle and outer myometrium as internal references for differentiating uterine sarcomas from leiomyomas at 3T MRI.Cancer imaging : the official publication of the International Cancer Imaging Society · 2019Article
- Moving Toward Individualized Medicine for Uterine Leiomyomas.Obstetrics and gynecology · 2018Article
- Frequency of uterine sarcomas in patients admitted for uterine fibroid surgery.Journal of the Turkish German Gynecological Association · 2017Article
- Is Laparoscopic Power Morcellation of Fibroids a Cardinal Sin in 2017?Journal of obstetrics and gynaecology of India · 2017Article
- Uterine fibroid management: from the present to the future.Human reproduction update · 2016Review
- Laparoscopic surgery on broken points for uterine sarcoma in the early stage decrease prognosis.Scientific reports · 2016Review
- Morcellation of apparent benign uterine myoma: assessing risk to benefit ratio.Journal of gynecologic oncology · 2016Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The U.S. Food and Drug Administration (FDA) is warning against the use of laparoscopic power morcellators in the majority of women undergoing myomectomy or hysterectomy for the treatment of leiomyomas because of the concern for inadvertent spread of tumor cells if an undiagnosed cancer were present. The authors, representing a 45-member review group, reviewed the current literature to formulate prevalence rates of leiomyosarcoma in women with presumed leiomyomas and to asses reliable data regarding patient survival after morcellation. The authors disagree with the FDA's methodology in reaching their conclusion and provide clinical recommendations for care of women with leiomyomas who are planning surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.