Evidence map›Paper›PMID 26646114›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias2016

Neuropsychological and Neuroanatomical Correlates of the Social Norms Questionnaire in Frontotemporal Dementia Versus Alzheimer's Disease.

Hemali Panchal, Pongsatorn Paholpak, Grace Lee, Andrew Carr, Joseph P Barsuglia, Michelle Mather, Elvira Jimenez, Mario F Mendez

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03507257 active not recruitingnot on this mapstarted 2018, after this paper: background citation

Longitudinal Early-onset Alzheimer's Disease Study Protocol

TypeobservationalSponsorIndiana UniversityRan2018 to 2027Enrolled850ConditionsEarly Onset Alzheimer Disease, Alzheimer Disease, Mild Cognitive ImpairmentArmsFlortaucipir, Florbetaben, Fluorodeoxyglucose
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Appreciation of Social Norms in Agenesis of the Corpus Callosum.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2021
    Article
  7. A Critical Review of Behavioral and Emotional Disinhibition.The Journal of nervous and mental disease · 2020
    Review
  8. Article
  9. Article
  10. Vicarious Embarrassment or "Fremdscham": Overendorsement in Frontotemporal Dementia.The Journal of neuropsychiatry and clinical neurosciences · 2020
    Article
  11. Article
  12. Review
  13. Article
  14. The attribution of animacy and agency in frontotemporal dementia versus Alzheimer's disease.Cortex; a journal devoted to the study of the nervous system and behavior · 2017
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Hemali PanchalVA Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, Los Angeles, CA, USA hpanchal@g.ucla.edu.
Pongsatorn PaholpakVA Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, Los Angeles, CA, USA Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, CA, USA Department of Psychiatry, Khon Kaen University, Khon Khaen, Thailand.
Grace LeeDepartment of Psychology, School of Behavioral Health, Loma Linda, CA, USA.
Andrew CarrVA Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
Joseph P BarsugliaVA Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
Michelle MatherVA Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, Los Angeles, CA, USA.
Elvira JimenezVA Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, Los Angeles, CA, USA Department of Psychiatry & Biobehavioral Sciences, Los Angeles, CA, USA.
Mario F MendezVA Greater Los Angeles Healthcare System, Los Angeles, CA, USA Department of Neurology, Los Angeles, CA, USA Department of Psychiatry & Biobehavioral Sciences, Los Angeles, CA, USA.
University of California, Los Angeles · USVA Greater Los Angeles Healthcare System · USKhon Kaen University · THLoma Linda University · USNeurobehavioral Systems · US

Funding

Multidisciplinary Study of Social Behavior and Emotion in Frontotemporal DementiaR01AG034499 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MENDEZ, MARIO F. · 2009 to 2013
$1.9M
NIA NIH HHS R01 AG034499
6 · The paper itself

Abstract

Traditional neuropsychological batteries may not distinguish early behavioral variant frontotemporal dementia (bvFTD) from Alzheimer's disease (AD) without the inclusion of a social behavioral measure. We compared 33 participants, 15 bvFTD, and 18 matched patients with early-onset AD (eAD), on the Social Norms Questionnaire (SNQ), neuropsychological tests and 3-dimensional T1-weighted magnetic resonance imaging (MRI). The analyses included correlations of SNQ results (total score, overendorsement or "overadhere" errors, and violations or "break" errors) with neuropsychological results and tensor-based morphometry regions of interest. Patients with BvFTD had significantly lower SNQ total scores and higher overadhere errors than patients with eAD. On neuropsychological measures, the SNQ total scores correlated significantly with semantic knowledge and the overadhere subscores with executive dysfunction. On MRI analysis, the break subscores significantly correlated with lower volume of lateral anterior temporal lobes (aTL). The results also suggest that endorsement of social norm violations corresponds to the role of the right aTL in social semantic knowledge.

Indexed as

Social NormsAlzheimer DiseaseFrontotemporal DementiaHumansMagnetic Resonance ImagingMiddle AgedNeuropsychological TestsSemanticsSurveys and QuestionnairesTemporal Lobeanterior temporal lobe Alzheimer’s diseasebehavioral variant frontotemporal dementiasocial normstensor-based morphometry

Identifiers

PMID26646114
PMCPMC10852706
OpenAlexW2196139745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.