Evidence map›Paper›PMID 26645813›Full record

ArticleEndocrine2016

Effects of combination treatment with sirolimus and mitotane on growth of human adrenocortical carcinoma cells.

Maria Cristina De Martino, Peter M van Koetsveld, Richard A Feelders, Steven W J Lamberts, Wouter W de Herder, Annamaria Colao, Rosario Pivonello, Leo J Hofland

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Endocrine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. SIRT1 is involved in adrenocortical cancer growth and motility.Journal of cellular and molecular medicine · 2021
    Article
  2. The effects of mitotane and 1α,25-dihydroxyvitamin DJournal of endocrinological investigation · 2020
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria Cristina De MartinoDivision of Endocrinology, Department of Internal Medicine, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.
Peter M van KoetsveldDivision of Endocrinology, Department of Internal Medicine, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.
Richard A FeeldersDivision of Endocrinology, Department of Internal Medicine, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.
Steven W J LambertsDivision of Endocrinology, Department of Internal Medicine, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.
Wouter W de HerderDivision of Endocrinology, Department of Internal Medicine, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.
Annamaria ColaoDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Uniniversità Federico II di Napoli, Via S. Pansini 5, 80131, Naples, Italy.
Rosario PivonelloDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Uniniversità Federico II di Napoli, Via S. Pansini 5, 80131, Naples, Italy.
Leo J HoflandDivision of Endocrinology, Department of Internal Medicine, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands. l.hofland@erasmusmc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical CarcinomaAntineoplastic Agents, HormonalCell Line, TumorCell ProliferationDose-Response Relationship, DrugHumansMitotaneSirolimusAntineoplastic Agents, HormonalMitotaneSirolimus

Identifiers

PMID26645813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.