Evidence map›Paper›PMID 26645697›Full record

SynthesisSports medicine (Auckland, N.Z.)2016

The Effects of Ischemic Preconditioning on Human Exercise Performance.

Anthony V Incognito, Jamie F Burr, Philip J Millar

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. Ischemic Preconditioning Improves Handgrip Strength and Functional Capacity in Active Elderly Women.International journal of environmental research and public health · 2022
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  19. The Acute Impact of External Compression on Back Squat Performance in Competitive Athletes.International journal of environmental research and public health · 2020
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anthony V IncognitoDepartment of Human Health and Nutritional Sciences, University of Guelph, 50 Stone Road East, Guelph, ON, N1G2W1, Canada.
Jamie F BurrDepartment of Human Health and Nutritional Sciences, University of Guelph, 50 Stone Road East, Guelph, ON, N1G2W1, Canada.
Philip J MillarDepartment of Human Health and Nutritional Sciences, University of Guelph, 50 Stone Road East, Guelph, ON, N1G2W1, Canada. pmillar@uoguelph.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIschemic preconditioning (IPC) is the exposure to brief periods of circulatory occlusion and reperfusion in order to protect local or systemic organs against subsequent bouts of ischemia. IPC has also been proposed as a novel intervention to improve exercise performance in healthy and diseased populations.

objectiveThe purpose of this systematic review is to analyze the evidence for IPC improving exercise performance in healthy humans.

methodsData were obtained using a systematic computer-assisted search of four electronic databases (MEDLINE, PubMed, SPORTDiscus, CINAHL), from January 1985 to October 2015, and relevant reference lists.

resultsTwenty-one studies met the inclusion criteria. The collective data suggest that IPC is a safe intervention that may be capable of improving time-trial performance. Available individual data from included studies demonstrate that IPC improved time-trial performance in 67% of participants, with comparable results in athletes and recreationally active populations. The effects of IPC on power output, oxygen consumption, rating of perceived exertion, blood lactate accumulation, and cardiorespiratory measures are unclear. The within-study heterogeneity may suggest the presence of IPC responders and non-responders, which in combination with small sample sizes, likely confound interpretation of mean group data in the literature.

conclusionThe ability of IPC to improve time-trial performance is promising, but the potential mechanisms responsible require further investigation. Future work should be directed toward identifying the individual phenotype and protocol that will best exploit IPC-mediated exercise performance improvements, facilitating its application in sport settings.

Indexed as

Athletic PerformanceExerciseIschemic PreconditioningCardiorespiratory FitnessExercise TestHumansLactic AcidOxygen ConsumptionLactic Acid

Identifiers

PMID26645697

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.