Evidence map›Paper›PMID 26645456›Full record

ArticlePlant physiology2016

Maize reas1 Mutant Stimulates Ribosome Use Efficiency and Triggers Distinct Transcriptional and Translational Responses.

Weiwei Qi, Jie Zhu, Qiao Wu, Qun Wang, Xia Li, Dongsheng Yao, Ying Jin, Gang Wang, Guifeng Wang, Rentao Song

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. MaizeInternational journal of molecular sciences · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Maize kernel development.Molecular breeding : new strategies in plant improvement · 2021
    Review
  18. A SnRK1-The Plant cell · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Weiwei QiShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Jie ZhuShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Qiao WuShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Qun WangShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Xia LiShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Dongsheng YaoShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Ying JinShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Gang WangShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Guifeng WangShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S).
Rentao SongShanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai 200444, China (W.Q., J.Z., Q.Wu., Q.Wa., X.L., D.Y., Y.J., Ga.W., Gu.W., R.S.); and Coordinated Crop Biology Research Center, Beijing 100193, China (W.Q., Ga.W., Gu.W., R.S.) and National Maize Improvement Center of China, China Agricultural University, Beijing, 100193, China (R.S) rentaosong@staff.shu.edu.cn.ORCID http://orcid.org/0000-0003-1810-9875
Shanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ribosome biogenesis is a fundamental cellular process in all cells. Impaired ribosome biogenesis causes developmental defects; however, its molecular and cellular bases are not fully understood. We cloned a gene responsible for a maize (Zea mays) small seed mutant, dek* (for defective kernel), and found that it encodes Ribosome export associated1 (ZmReas1). Reas1 is an AAA-ATPase that controls 60S ribosome export from the nucleus to the cytoplasm after ribosome maturation. dek* is a weak mutant allele with decreased Reas1 function. In dek* cells, mature 60S ribosome subunits are reduced in the nucleus and cytoplasm, but the proportion of actively translating polyribosomes in cytosol is significantly increased. Reduced phosphorylation of eukaryotic initiation factor 2α and the increased elongation factor 1α level indicate an enhancement of general translational efficiency in dek* cells. The mutation also triggers dramatic changes in differentially transcribed genes and differentially translated RNAs. Discrepancy was observed between differentially transcribed genes and differentially translated RNAs, indicating distinct cellular responses at transcription and translation levels to the stress of defective ribosome processing. DNA replication and nucleosome assembly-related gene expression are selectively suppressed at the translational level, resulting in inhibited cell growth and proliferation in dek* cells. This study provides insight into cellular responses due to impaired ribosome biogenesis.

Indexed as

Protein BiosynthesisTranscription, GeneticCell ProliferationCloning, MolecularConserved SequenceDown-RegulationGene Expression Regulation, PlantGene OntologyGenes, PlantModels, BiologicalMutationNucleosomesPhenotypePhylogenyRibosomesRibosome Subunits, Large, EukaryoticNucleosomes

Identifiers

PMID26645456
PMCPMC4734584
OpenAlexW2257508845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.