Evidence map›Paper›PMID 26645194›Full record

ArticleScientific data2015

Hair-bundle proteomes of avian and mammalian inner-ear utricles.

Phillip A Wilmarth, Jocelyn F Krey, Jung-Bum Shin, Dongseok Choi, Larry L David, Peter G Barr-Gillespie

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular Composition of Vestibular Hair Bundles.Cold Spring Harbor perspectives in medicine · 2019
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Phillip A WilmarthDepartment of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, OR, USA.
Jocelyn F KreyOregon Hearing Research Center &Vollum Institute, Oregon Health &Science University, Portland, OR, USA.
Jung-Bum ShinDepartment of Neuroscience, University of Virginia, Charlottesville, VA, USA.
Dongseok ChoiDepartment of Public Health &Preventive Medicine, Oregon Health &Science University, Portland, OR, USA.
Larry L DavidDepartment of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, OR, USA.
Peter G Barr-GillespieDepartment of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0002-9787-5860
Oregon Health & Science University · USUniversity of Virginia · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4M
Hair-Bundle ProteinsR01DC002368 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Peter Gordon Barr-Gillespie · 1994 to 2026
$11.3M
PORTLAND AREA COMMUNICATION RESEARCH CORE CENTERP30DC005983 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI BARR-GILLESPIE, PETER GORDON · 2003 to 2017
$9.0M
Hair Bundle Structure and DynamicsR01DC011034 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI BARR-GILLESPIE, PETER GORDON · 2010 to 2024
$6.4M
PROTEIN CLEAVAGE SITES IN EXPERIMENTAL CATARACTOUS LENSR01EY007755 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI DAVID, LARRY L · 1995 to 2014
$3.6M
Global analysis of bundle protein transport in mouse vestibular hair cellsF32DC012455 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI KREY, JOCELYN F · 2012 to 2013
$106k
PROTEIN CLEAVAGE SITES IN EXPERIMENTAL CATARACTOUS LENSER29EY007755 · NEI · OREGON HEALTH AND SCIENCE UNIVERSITY · PI DAVID, LARRY L · 1989 to 1993
–
NEI NIH HHS EY007755NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY007755NIDCD NIH HHS F32 DC012455NIDCD NIH HHS P30 DC005983NIDCD NIH HHS R01 DC002368NIDCD NIH HHS R01 DC011034
6 · The paper itself

Abstract

Examination of multiple proteomics datasets within or between species increases the reliability of protein identification. We report here proteomes of inner-ear hair bundles from three species (chick, mouse, and rat), which were collected on LTQ or LTQ Velos ion-trap mass spectrometers; the constituent proteins were quantified using MS2 intensities, which are the summed intensities of all peptide fragmentation spectra matched to a protein. The data are available via ProteomeXchange with identifiers PXD002410 (chick LTQ), PXD002414 (chick Velos), PXD002415 (mouse Velos), and PXD002416 (rat LTQ). The two chick bundle datasets compared favourably to a third, already-described chick bundle dataset, which was quantified using MS1 peak intensities, the summed intensities of peptides identified by high-resolution mass spectrometry (PXD000104; updated analysis in PXD002445). The mouse bundle dataset described here was comparable to a different mouse bundle dataset quantified using MS1 intensities (PXD002167). These six datasets will be useful for identifying the core proteome of vestibular hair bundles.

Indexed as

Hair Cells, VestibularProteomeSaccule and UtricleAnimalsChickensMiceProteomicsRatsSpecies SpecificityProteome

Identifiers

PMID26645194
PMCPMC4672683
OpenAlexW2249084272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.