Evidence map›Paper›PMID 26645001›Full record

ReviewGland surgery2015

Oncological safety of prophylactic breast surgery: skin-sparing and nipple-sparing versus total mastectomy.

Victorien M T van Verschuer, Marike C Maijers, Carolien H M van Deurzen, Linetta B Koppert

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gland surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03627442 (Pilot Study), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03627442 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Pilot Study: Post-operative Outcomes of Enhanced Energy Delivery Dissection for Mastectomy Breast Flap Creation With Immediate Breast Reconstruction

TypeinterventionalSponsorInvuity, Inc.Ran2018 to 2019Enrolled15ConditionsBreast CancerArmsMastectomy with PhotonBlade, Mastectomy with Bovie
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Victorien M T van Verschuer1 Erasmus MC Cancer Institute, Department of Surgical Oncology, Rotterdam, the Netherlands ; 2 VUmc, Department of Plastic and Reconstructive Surgery, Amsterdam, the Netherlands ; 3 Erasmus MC Cancer Institute, Department of Pathology, Rotterdam, the Netherlands.
Marike C Maijers1 Erasmus MC Cancer Institute, Department of Surgical Oncology, Rotterdam, the Netherlands ; 2 VUmc, Department of Plastic and Reconstructive Surgery, Amsterdam, the Netherlands ; 3 Erasmus MC Cancer Institute, Department of Pathology, Rotterdam, the Netherlands.
Carolien H M van Deurzen1 Erasmus MC Cancer Institute, Department of Surgical Oncology, Rotterdam, the Netherlands ; 2 VUmc, Department of Plastic and Reconstructive Surgery, Amsterdam, the Netherlands ; 3 Erasmus MC Cancer Institute, Department of Pathology, Rotterdam, the Netherlands.
Linetta B Koppert1 Erasmus MC Cancer Institute, Department of Surgical Oncology, Rotterdam, the Netherlands ; 2 VUmc, Department of Plastic and Reconstructive Surgery, Amsterdam, the Netherlands ; 3 Erasmus MC Cancer Institute, Department of Pathology, Rotterdam, the Netherlands.
Erasmus MC Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women with a BRCA1/2 gene mutation and others with a high breast cancer risk may opt for bilateral prophylactic mastectomy. To allow for immediate breast reconstruction the skin envelope is left in situ with or without the nipple-areola complex (NAC). Although possibly leading to a more natural aesthetic outcome than the conventional total mastectomy, so-called skin-sparing mastectomies (SSM) and nipple-sparing mastectomies (NSM) may leave some breast glandular tissue in situ. The oncological risk associated with remaining breast glandular tissue is unclear. We present a case of primary breast cancer after prophylactic mastectomy followed by a review of the literature on remaining breast glandular tissue after various mastectomy techniques and oncological safety of prophylactic mastectomies.

Indexed as

breast glandular tissuenipple-sparing mastectomy (NSM)primary breast cancerRisk-reductionskin-sparing mastectomy (SSM)terminal duct lobular unitstotal mastectomy

Identifiers

PMID26645001
PMCPMC4647001
OpenAlexW2191119042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.