Evidence map›Paper›PMID 26644399›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2016

A framework for self-experimentation in personalized health.

Ravi Karkar, Jasmine Zia, Roger Vilardaga, Sonali R Mishra, James Fogarty, Sean A Munson, Julie A Kientz

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Trial
  2. Article
  3. Informing the Design of Individualized Self-Management Regimens from the Human, Data, and Machine Learning Perspectives.ACM transactions on computer-human interaction : a publication of the Association for Computing Machinery · 2025
    Article
  4. Article
  5. Tracking and its Potential for Older Adults with Memory Concerns.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2025
    Article
  6. MigraineTracker: Examining Patient Experiences with Goal-Directed Self-Tracking for a Chronic Health Condition.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2024
    Article
  7. Approaches to Tailoring Between-Session Mental Health Therapy Activities.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Donating Health Data to Research: Influential Characteristics of Individuals Engaging in Self-Tracking.International journal of environmental research and public health · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. "They don't always think about that": Translational Needs in the Design of Personal Health Informatics Applications.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2021
    Article
  19. From Reflection to Action: Combining Machine Learning with Expert Knowledge for Nutrition Goal Recommendations.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ravi KarkarComputer Science & Engineering, University of Washington, Seattle, WA, USA.
Jasmine ZiaDivision of Gastroenterology, Medicine University of Washington, Seattle, WA, USA.
Roger VilardagaPsychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Sonali R MishraInformation School, University of Washington, Seattle, WA, USA.
James FogartyComputer Science & Engineering, University of Washington, Seattle, WA, USA.
Sean A MunsonHuman Centered Design & Engineering, University of Washington, Seattle, WA, USA.
Julie A KientzHuman Centered Design & Engineering, University of Washington, Seattle, WA, USA.

Funding

Innovative Smartphone Application for Quitting Smoking among Seriously Mentally IK99DA037276 · NIDA · UNIVERSITY OF WASHINGTON · PI VILARDAGA, ROGER · 2014 to 2015
$344k
Sharing Patient Lifelog Data with the Primary Care Team for Two Patient Populations: Preventative Care & Chronic Disease ManagementR21HS023654 · AHRQ · UNIVERSITY OF WASHINGTON · PI MUNSON, SEAN · 2014 to 2015
$297k
NIDA NIH HHS K99 DA037276
6 · The paper itself

Abstract

objectiveTo describe an interdisciplinary and methodological framework for applying single case study designs to self-experimentation in personalized health. The authors examine the framework's applicability to various health conditions and present an initial case study with irritable bowel syndrome (IBS). METHODS AND MATERIALS: An in-depth literature review was performed to develop the framework and to identify absolute and desired health condition requirements for the application of this framework. The authors developed mobile application prototypes, storyboards, and process flows of the framework using IBS as the case study. The authors conducted three focus groups and an online survey using a human-centered design approach for assessing the framework's feasibility.

resultsAll 6 focus group participants had a positive view about our framework and volunteered to participate in future studies. Most stated they would trust the results because it was their own data being analyzed. They were most concerned about confounds, nonmeaningful measures, and erroneous assumptions on the timing of trigger effects. Survey respondents (N = 60) were more likely to be adherent to an 8- vs 12-day study length even if it meant lower confidence results. DISCUSSION: Implementation of the self-experimentation framework in a mobile application appears to be feasible for people with IBS. This framework can likely be applied to other health conditions. Considerations include the learning curve for teaching self-experimentation to non-experts and the challenges involved in operationalizing and customizing study designs.

conclusionUsing mobile technology to guide people through self-experimentation to investigate health questions is a feasible and promising approach to advancing personalized health.

Indexed as

AutoexperimentationIrritable Bowel SyndromeMobile ApplicationsPrecision MedicineFeasibility StudiesFemaleFocus GroupsHumansMaleSurveys and Questionnaireshuman-centered designindividualized medicineirritable bowel syndromeself-experimentationtechnology

Identifiers

PMID26644399
PMCPMC6095104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.