Trial reportGynecologic oncology2016
The use of novel technology-based weight loss interventions for obese women with endometrial hyperplasia and cancer.
Trial report in Gynecologic oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03394638 (Assessing the Value of eHealth for Bariatric Surgery), which is not on this map. Cited by 32 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessing the Value of eHealth for Bariatric Surgery
Who cites it
32 citing papers in PubMed, 7 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- A systematic review of influences on engagement with remote health interventions targeting weight management for individuals living with excess weight.International journal of obesity (2005) · 2025Pooled it
- Interventions for weight reduction in obesity to improve survival in women with endometrial cancer.The Cochrane database of systematic reviews · 2023Pooled it
- Pooled it
- Telehealth Interventions to Improve Obstetric and Gynecologic Health Outcomes: A Systematic Review.Obstetrics and gynecology · 2020Pooled it
- Systematic Review of Randomized Controlled Trials of Exercise Interventions Using Digital Activity Trackers in Patients With Cancer.Journal of the National Comprehensive Cancer Network : JNCCN · 2019Pooled it
- Toward the optimal strategy for sustained weight loss in overweight cancer survivors: a systematic review of the literature.Journal of cancer survivorship : research and practice · 2017Pooled it
- Weight Loss Randomized Intervention Trials in Female Cancer Survivors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016Pooled it
- Feasibility of an exercise-nutrition-psychology integrated rehabilitation model based on mobile health and virtual reality for cancer patients: a single-center, single-arm, prospective phase II study.BMC palliative care · 2024Trial
- Randomized trial of a clinic-based weight loss intervention in cancer survivors.Journal of cancer survivorship : research and practice · 2018Trial
- A Randomized, Controlled, Multicenter Study of Technology-Based Weight Loss Interventions among Endometrial Cancer Survivors.Obesity (Silver Spring, Md.) · 2017Trial
- Multimodal (Bio)Markers and Risk of Obesity - A Comprehensive Scoping Review.Advances in nutrition (Bethesda, Md.) · 2026Article
- Metformin combined with progesterone improves efficacy and reduces adverse reactions in early endometrial cancer.American journal of translational research · 2026Article
- Just-In-Time Adaptive Interventions for Weight Management Among Adults With Excess Body Weight: Scoping Review.Journal of medical Internet research · 2025Article
- Obesity management in the setting of endometrial cancer and hyperplasia: A narrative review.Gynecologic oncology reports · 2025Review
- Pregnancy outcomes of endometrial hyperplasia with or without atypia.Scientific reports · 2025Article
- Effectiveness of Telehealth in Obstetric and Gynecologic Care: A Systematic Review of Health Outcomes.Cureus · 2024Review
- Adaptations to a statewide walking program: Use of iterative feedback cycles between research and delivery systems improves fit for over 10 years.Translational behavioral medicine · 2024Article
- Perceived importance of weight loss and exercise among endometrial cancer survivors with overweight or obesity: Implications for lifestyle modification interventions.Obesity science & practice · 2023Article
- Digital Health Interventions for Adult Patients With Cancer Evaluated in Randomized Controlled Trials: Scoping Review.Journal of medical Internet research · 2023Article
- Higher baseline BMI and lower estimated median income is associated with increasing BMI after endometrial cancer diagnosis.Gynecologic oncology reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveObesity significantly increases the risk of the development of both endometrial hyperplasia and cancer. Our objective was to assess the feasibility of two technology-based weight loss interventions in this patient population.
methodsWomen with obesity (BMI≥30kg/m(2)) and endometrial hyperplasia or Type I endometrial cancer were randomized 1:1 to a technology-based 6month lifestyle intervention via either telemedicine or text messaging. The telemedicine arm received weekly phone calls, with weights tracked online using Withings© Wi-Fi scales. The text arm received 3-5 personalized messages daily via Text4Diet™. Participants maintained a 1200-1800calorie/day diet, self-monitored food intake and received exercise goals. Biomarkers (IGFBP-1, adiponectin, VEGF, IL1-beta, IL2, IL6, and IL7) were assessed pre- and post-treatment.
resultsTwenty women were randomized (Telemedicine: n=10, Text4Diet: n=10), and 90% lost weight. Many were early stage (70%) and grade (43.8%) disease with a median age of 60.5years. We observed a statistically greater weight loss in the Telemedicine arm [median loss: 9.7kg (range: 1.6-22.9kg)] versus 3.9kg (range: 0.3-11.4kg) in the Text4Diet arm (p=0.0231). Similarly, percent weight loss was greater in the Telemedicine (7.6%) as compared to the Text4Diet arm (4.1%, p=0.014). Mean serum levels of IL-2 were significantly (27.15pg/mL vs. 5.18pg/mL, p=0.0495) lower at intervention end as compared to baseline.
conclusionsA technology-based weight loss intervention is feasible in women with Type I endometrial cancer/hyperplasia. Both interventions produced weight loss, although more person-to-person contact produced more significant outcomes. Reductions in expression of IL-2 were related to weight loss.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.