ArticleScientific reports2015
From cholera to corals: Viruses as drivers of virulence in a major coral bacterial pathogen.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 81 citations in OpenAlex.
- Temperate and filamentous bacteriophages as reservoirs of bacterial virulence in stony coral tissue loss disease.Coral reefs (Online) · 2026Article
- Viral activity in lake analogs of anoxic early Earth oceans.Microbiome · 2025Article
- The coral microbiome in sickness, in health and in a changing world.Nature reviews. Microbiology · 2024Review
- Unlocking the genomic potential of Red Sea coral probiotics.Scientific reports · 2024Article
- Globally distributed bacteriophage genomes reveal mechanisms of tripartite phage-bacteria-coral interactions.The ISME journal · 2024Article
- Host-specific viral predation network on coral reefs.The ISME journal · 2024Article
- Characterization of a Filamentous Phage, Vaf1, fromApplied and environmental microbiology · 2023Article
- Viruses of a key coral symbiont exhibit temperature-driven productivity across a reefscape.ISME communications · 2023Article
- Effects of Ocean Warming on the Underexplored Members of the Coral Microbiome.Integrative and comparative biology · 2022Review
- Isolation and characterization of a Vibrio owensii phage phi50-12.Scientific reports · 2022Article
- Thermal stress triggers productive viral infection of a key coral reef symbiont.The ISME journal · 2022Article
- Revisiting the rules of life for viruses of microorganisms.Nature reviews. Microbiology · 2021Review
- Insights into the Cultured Bacterial Fraction of Corals.mSystems · 2021Article
- Article
- Closely RelatedViruses · 2020Article
- Defining Coral Bleaching as a Microbial Dysbiosis within the Coral Holobiont.Microorganisms · 2020Review
- Beyond Cholera: Characterization ofViruses · 2020Article
- A multiomic analysis of in situ coral-turf algal interactions.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Article
- Genomic and ecological attributes of marine bacteriophages encoding bacterial virulence genes.BMC genomics · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disease is an increasing threat to reef-building corals. One of the few identified pathogens of coral disease is the bacterium Vibrio coralliilyticus. In Vibrio cholerae, infection by a bacterial virus (bacteriophage) results in the conversion of non-pathogenic strains to pathogenic strains and this can lead to cholera pandemics. Pathogenicity islands encoded in the V. cholerae genome play an important role in pathogenesis. Here we analyse five whole genome sequences of V. coralliilyticus to examine whether virulence is similarly driven by horizontally acquired elements. We demonstrate that bacteriophage genomes encoding toxin genes with homology to those found in pathogenic V. cholerae are integrated in V. coralliilyticus genomes. Virulence factors located on chromosomal pathogenicity islands also exist in some strains of V. coralliilyticus. The presence of these genetic signatures indicates virulence in V. coralliilyticus is driven by prophages and other horizontally acquired elements. Screening for pathogens of coral disease should target conserved regions in these elements.
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