ArticleClinical and translational science2015
Research START: A Multimethod Study of Barriers and Accelerators of Recruiting Research Participants.
Article in Clinical and translational science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Recruitment and enrollment of participants in an online diabetes self-management intervention in a virtual environment.Contemporary clinical trials · 2021Trial
- Parental perspectives and willingness towards digital paediatric research: a cross-sectional survey in two Chinese cities.BMJ open · 2026Article
- A data-driven approach to optimizing clinical study eligibility criteria.Journal of biomedical informatics · 2023Article
- Uncovering key clinical trial features influencing recruitment.Journal of clinical and translational science · 2023Article
- Using a Patient Portal to Increase Enrollment in a Newborn Screening Research Study: Observational Study.JMIR pediatrics and parenting · 2022Article
- Recruitment cost and outcomes for an arthritis work disability prevention randomized clinical trial: The Work It study.Contemporary clinical trials communications · 2021Article
- "Include me if you can"-reasons for low enrollment of pediatric patients in a psychopharmacological trial.Trials · 2021Article
- Factors Associated With the Acceleration of Patient Enrollment in Clinical Studies: A Cross-Sectional Study.Frontiers in pharmacology · 2021Article
- EHR phenotyping for research recruitment: Researcher, IRB, and physician perspectives on approaches to contacting patients.Journal of clinical and translational science · 2020Article
- Knowledge and use of recruitment support tools among study coordinators at an academic medical center: The Novel Approaches to Recruitment Planning Study.Contemporary clinical trials communications · 2019Article
- Patient perspectives on use of electronic health records for research recruitment.BMC medical research methodology · 2019Article
- Two-step recruitment process optimizes retention in FLEX clinical trial.Contemporary clinical trials communications · 2018Article
- Assessment of a shortened informed consent form for pediatric research: a pilot study.Pediatric research · 2018Article
- An initiative using informatics to facilitate clinical research planning and recruitment in the VA health care system.Contemporary clinical trials communications · 2018Article
- Discontinuation of a randomised controlled trial in general practice due to unsuccessful patient recruitment.BJGP open · 2017Article
- A cross-cutting approach to enhancing clinical trial site success: The Department of Veterans Affairs' Network of Dedicated Enrollment Sites (NODES) model.Contemporary clinical trials communications · 2017Article
- Barriers and Facilitating Factors for Research Involvement in Cancer Centers: A Survey of Colorectal Cancer Center Coordinators in Germany, Austria, and Switzerland.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Under-recruitment into clinical trials is a common and costly problem that undermines medical research. To better understand barriers to recruitment into clinical trials in our region, we conducted a multimethod descriptive study. We initially surveyed investigators who had conducted or were currently conducting studies that utilized an adult or pediatric clinical research center (n = 92). We then conducted focus groups and key informant interviews with investigators, coordinators, and other stakeholders in clinical and translational research (n = 32 individuals). Only 41% of respondents reported that they had or were successfully meeting recruitment goals and 24% of the closed studies actually met their targeted recruitment goals. Varied reasons were identified for poor recruitment but there was not a single investigator or study "phenotype" that predicted enrollment outcome. Investigators commonly recruited from their own practice or clinic, and 29% used a manual electronic medical record search. The majority of investigators would utilize a service that provides recruitment advice, including feasibility assessment and consultation, easier access to the electronic health record and assistance with institutional review board and other regulatory requirements. Our findings suggest potential benefits providing assistance across a range of services that can be individualized to the varied needs of clinical and translational investigators.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.