Evidence map›Paper›PMID 26643401›Full record

Trial reportBurns : journal of the International Society for Burn Injuries2016

Effects of community-based exercise in children with severe burns: A randomized trial.

Raquel Peña, Leybi L Ramirez, Craig G Crandall, Steven E Wolf, David N Herndon, Oscar E Suman

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Burns : journal of the International Society for Burn Injuries, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Effects of different duration exercise programs in children with severe burns.Burns : journal of the International Society for Burn Injuries · 2017
    Trial
  5. Key Exercise Concepts in the Rehabilitation from Severe Burns.Physical medicine and rehabilitation clinics of North America · 2023
    Review
  6. Rehabilitative Exercise Training for Burn Injury.Sports medicine (Auckland, N.Z.) · 2021
    Review
  7. Article
  8. Cardiac Structure and Function in Well-Healed Burn Survivors.Journal of burn care & research : official publication of the American Burn Association · 2019
    Article
  9. Rehabilitation Exercise Increases Physical Activity Levels in Severely Burned Children While Improving Aerobic Exercise Capacity and Strength.Journal of burn care & research : official publication of the American Burn Association · 2018
    Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raquel PeñaDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, United States; Shriners Hospitals for Children, Galveston, TX, United States.
Leybi L RamirezDepartment of Developmental Nutrition, Physical Activity and Energy Metabolism, University of Arkansas for The Medical Science, Little Rock, AR, United States; Arkansas Children Hospital Research Institute, Little Rock, AR, United States.
Craig G CrandallInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and University of Texas Southwestern Medical Center, Dallas, TX, United States.
Steven E WolfDivision of Burns, Trauma, and Critical Care, Department of Surgery University of Texas Southwestern, Dallas, TX, United States.
David N HerndonDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, United States; Shriners Hospitals for Children, Galveston, TX, United States.
Oscar E SumanDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, United States; Shriners Hospitals for Children, Galveston, TX, United States. Electronic address: oesuman@utmb.edu.

Funding

Project 9: The role of androgen/corticosteroid in fat, muscle and glucose metabolism of burn victimsP50GM060338 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI HERNDON, DAVID N. · 2000 to 2017
$24.2M
Oxandrolone and Exercise: A potent therapy in the rehabilitation from burnsR01HD049471 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SUMAN-VEJAS, OSCAR E. · 2006 to 2019
$5.8M
SIGNALING BY FRIZZLED PROTEINS IN DROSOPHILAR01GM060388 · NIGMS · STANFORD UNIVERSITY · PI NUSSE, ROEL · 2000 to 2003
$381k
NICHD NIH HHS R01 HD049471NICHD NIH HHS R01-HD049471NICHD NIH HHS R01-HD049471-08S1NIGMS NIH HHS P50 GM060338NIGMS NIH HHS P50-GM060388NIGMS NIH HHS R01 GM060388
6 · The paper itself

Abstract

objectiveTo counteract long-lasting muscle break down, muscle weakness, and poor physical fitness resulting from severe burns, we recommend a 12-week in-hospital exercise training rehabilitation program. Unfortunately, this in-hospital training program requires time away from home, family, school or work. This study was undertaken to evaluate an alternative exercise rehabilitation strategy involving a 12-week community-based exercise training rehabilitation program (COMBEX) carried out at or near the patient and caretaker's home. STUDY DESIGN AND

participantsPediatric patients (7-18 years) with ≥ 30% of total body surface area (TBSA) burns were randomized to participate in COMBEX (N=12) or an outpatient exercise program (EX) at the hospital (N=22). Both programs were started after hospital discharge and consisted of 12 weeks of progressive resistive and aerobic exercise. COMBEX was performed in community fitness centers near the patients' home. Endpoints were assessed at discharge (pre-exercise) and after the 12-week program. Primary endpoints were lean body mass (dual energy X-ray absorptiometry), muscle strength (isokinetic dynamometry), and peak aerobic capacity (indirect calorimetry).

resultsDemographics, length of hospitalization, and TBSA burned were comparable between groups (P>0.05). Both groups exhibited a significant (P ≤ 0.01 for all) increase (mean ± SEM) in lean muscle mass (EX: 6.9 ± 1.7%; COMBEX: 6.5 ± 1.1%), muscle strength (EX: 67.1 ± 7.0%; COMBEX: 49.9 ± 6.8%), and peak aerobic capacity (EX: 35.5 ± 4.0%; COMBEX: 46.9 ± 7.7%). Furthermore, the magnitude of these increases were not different between groups (P>0.12).

conclusionsBoth EX and COMBEX are efficacious in improving lean mass, strength, and cardiopulmonary capacity in severely burned children.

Indexed as

AdolescentBody Surface AreaBurnsChildCommunity Health ServicesExercise TherapyExercise ToleranceFemaleHumansLength of StayMaleMuscle StrengthOxygen ConsumptionPhysical FitnessTrauma Severity IndicesTreatment OutcomeCommunity-based exercise programExercise programLean body massMuscle strengthPeak aerobic capacityRehabilitationStandard of care

Identifiers

PMID26643401
PMCPMC4724475

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.