Evidence map›Paper›PMID 26642901›Full record

ArticleTrends in microbiology2016

Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research.

Cynthia I Grossman, Anna Laura Ross, Judith D Auerbach, Jintanat Ananworanich, Karine Dubé, Joseph D Tucker, Veronica Noseda, Cristina Possas, Dianne M Rausch, International AIDS Society (IAS) ‘Towards an HIV Cure’ initiative

Abstract read
In one paragraph

Article in Trends in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Trial
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  4. The HIV Reservoir and Immune Landscape Across the Life Course of Women: Implications for Cure Strategies.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cynthia I Grossman5601 Fishers Lane Room 9G19, MSC 9831, National Institutes of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address: grossmanc@mail.nih.gov.
Anna Laura RossANRS, 101 rue de Tolbiac, 75013 Paris, France.
Judith D AuerbachCenter for AIDS Prevention Studies, Department of Medicine, School of Medicine, University of California, Mailcode 0886, 550 16th Street, 3rd Floor, San Francisco, CA 94158, USA.
Jintanat Ananworanich6720A Rockledge Drive, Suite 400, The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA.
Karine Dubé120 Mason Farm Road, #2047 Genetic Medicine Building, Institute of Global Health and Infectious Diseases (IGHID), Collaboratory of AIDS Researchers for Eradication (CARE), Chapel Hill, NC 27516, USA.
Joseph D TuckerUNC Project-China, 2 Lujing Road, Guangzhou, China, 510095; and University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Veronica NosedaSidaction, 228 rue Faubourg Saint-Martin, 75010 Paris, France.
Cristina PossasOswaldo Cruz Foundation, Evandro Chagas National Institute of Infectious Diseases and Bio-Manguinhos, Avenida Brazil 4365 Manguinhos, CEP 21040-360, Rio de Janeiro, Brazil.
Dianne M Rausch5601 Fishers Lane Room 9G19, MSC 9831, National Institutes of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
International AIDS Society (IAS) ‘Towards an HIV Cure’ initiative

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
Using NK Cells to eliminate the latent HIV reservoirU19AI096113 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OTT, MELANIE MARIA · 2011 to 2015
$39.5M
Intramural NIH HHS Z99 MH999999NIAID NIH HHS P30 AI050410NIAID NIH HHS P30-AI50410NIAID NIH HHS U19 AI096113NIMH NIH HHS P30 MH062246PHS HHS R01A108366-01
6 · The paper itself

Abstract

The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community.

Indexed as

Acquired Immunodeficiency SyndromeBiomedical ResearchClinical Trials as TopicCooperative BehaviorCost-Benefit AnalysisHIV InfectionsHumansInterdisciplinary CommunicationRemission InductionSocial Sciencescost-effectivenessethicsHIV curemultidisciplinarypublic understanding of science

Identifiers

PMID26642901
PMCPMC4698010

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.