Evidence map›Paper›PMID 26642758›Full record

ArticleBMC pulmonary medicine2015

Burkholderia cepacia complex: clinical course in cystic fibrosis patients.

Tania Wrobel Folescu, Claudia Henrique da Costa, Renata Wrobel Folescu Cohen, Orlando Carlos da Conceição Neto, Rodolpho Mattos Albano, Elizabeth Andrade Marques

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Epidemiology and Clinical Features of Burkholderia Bacteremia at a Hospital in India.The American journal of tropical medicine and hygiene · 2024
    Article
  4. Vaccines · 2024
    Review
  5. Frontiers in cellular and infection microbiology · 2024
    Article
  6. Phage therapy to treat cystic fibrosisFrontiers in microbiology · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Article
  15. Article
  16. Viruses · 2018
    Article
  17. Review
  18. Article
  19. Article
  20. Cystic Fibrosis Pulmonary Exacerbations Attributable to Respiratory Syncytial Virus and Influenza: A Population-Based Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tania Wrobel FolescuDepartment of Pediatric Pulmonology, Instituto Fernandes Figueira (Fundação Oswaldo Cruz, Ministério da Saúde), Av. Rui Barbosa, 716, 2nd floor, Flamengo, Zip Code: 22250-020, Rio de Janeiro, RJ, Brazil. taniafolescu@hotmail.com.
Claudia Henrique da CostaDepartment of Pulmonology, Universidade do Estado do Rio de Janeiro/UERJ, Rio de Janeiro, RJ, Brazil. ccosta.uerj@gmail.com.
Renata Wrobel Folescu CohenDepartment of Pediatric Pulmonology, Instituto Fernandes Figueira (Fundação Oswaldo Cruz, Ministério da Saúde), Av. Rui Barbosa, 716, 2nd floor, Flamengo, Zip Code: 22250-020, Rio de Janeiro, RJ, Brazil. renatawfc@gmail.com.
Orlando Carlos da Conceição NetoDepartment of Microbiology, Hospital Central da Aeronáutica, Rio de Janeiro, RJ, Brazil. orlandoccnetto@yahoo.com.br.
Rodolpho Mattos AlbanoDepartment of Biochemistry, Universidade do Estado do Rio de Janeiro/UERJ, Rio de Janeiro, RJ, Brazil. albano@uerj.br.
Elizabeth Andrade MarquesDepartment of Microbiology, Universidade do Estado do Rio de Janeiro/UERJ, Rio de Janeiro, RJ, Brazil. elizabethamarques@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary deterioration after B.cepacia complex (BCC) colonization has a heterogeneous pattern. The aim was to investigate the clinical outcome of BCC colonization in CF patients chronically colonized with P. aeruginosa.

methodsCF patients chronically colonized with P. aeruginosa were divided into three groups: intermittent (I), chronic (II) and no colonization (III) with BCC. Body mass index (BMI) percentile and spirometric parameters were analyzed at three different times in each group.

resultsFifty-six patients chronically colonized with P. aeruginosa were included. Of these, 27 also had evidence of BCC colonization (13 intermittent and 14 chronic). BMI percentile was significantly lower among patients chronically colonized by both P. aeruginosa and BCC. Mean values of FEV1 and FVC % were also significantly lower in these patients, both at the time of chronic BCC colonization and 24 months forward.

conclusionsChronic BCC colonization is associated with significant loss of lung function. Lower BMI might be a risk factor for chronic BCC colonization, preceding these events.

Indexed as

Burkholderia cepacia complexBody Mass IndexBurkholderia InfectionsCarrier StateCase-Control StudiesChildCoinfectionCystic FibrosisDisease ProgressionFemaleForced Expiratory VolumeHumansLongitudinal StudiesMalePseudomonas aeruginosaPseudomonas Infections

Identifiers

PMID26642758
PMCPMC4672471

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.