Evidence map›Paper›PMID 26640891›Full record

ArticlePloS one2015

The High Prevalence of Low HDL-Cholesterol Levels and Dyslipidemia in Rural Populations in Northwestern China.

Pengfei Ge, Caixia Dong, Xiaolan Ren, Elisabete Weiderpass, Chouji Zhang, Haoqiang Fan, Jing Zhang, Yongrui Zhang, Jinen Xi

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
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  6. Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2022
    Article
  7. Article
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  12. Association of theAging · 2020
    Observational
  13. Evaluation of health-related quality of life in adults with and without dyslipidaemia in rural areas of central China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 4 countries.

Pengfei GeInstitute of Non-communicable Chronic Diseases, Gansu Center for Disease Control and Prevention, 230 Donggang Western Road, Chengguan District, 730000, Lanzhou, Gansu Province, China.
Caixia DongInstitute of Non-communicable Chronic Diseases, Gansu Center for Disease Control and Prevention, 230 Donggang Western Road, Chengguan District, 730000, Lanzhou, Gansu Province, China.
Xiaolan RenInstitute of Non-communicable Chronic Diseases, Gansu Center for Disease Control and Prevention, 230 Donggang Western Road, Chengguan District, 730000, Lanzhou, Gansu Province, China.
Elisabete WeiderpassDepartment of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Chouji ZhangInstitute of Non-communicable Chronic Diseases, Gansu Center for Disease Control and Prevention, 230 Donggang Western Road, Chengguan District, 730000, Lanzhou, Gansu Province, China.
Haoqiang FanInstitute of Non-communicable Chronic Diseases, Gansu Center for Disease Control and Prevention, 230 Donggang Western Road, Chengguan District, 730000, Lanzhou, Gansu Province, China.
Jing ZhangInstitute of Non-communicable Chronic Diseases, Gansu Center for Disease Control and Prevention, 230 Donggang Western Road, Chengguan District, 730000, Lanzhou, Gansu Province, China.
Yongrui ZhangInstitute of Non-communicable Chronic Diseases, Gansu Center for Disease Control and Prevention, 230 Donggang Western Road, Chengguan District, 730000, Lanzhou, Gansu Province, China.
Jinen XiInstitute of Non-communicable Chronic Diseases, Gansu Center for Disease Control and Prevention, 230 Donggang Western Road, Chengguan District, 730000, Lanzhou, Gansu Province, China.
Gansu Provincial Center for Disease Control and Prevention · CNCancer Registry of Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDyslipidemia is a major health problem in China and an important modifiable cardiovascular disease (CVD) risk factor. This study aimed to describe the prevalence of dyslipidemia and low high density lipoprotein cholesterol (HDL-cholesterol) and associated risk factors among adults in rural northwest China.

methodsIn a cross-sectional analyses involving 2,980 adults aged >18 years, information on the demographics, cigarette smoking, alcohol consumption, education, and medical history was collected via face-to-face interviews. Blood samples were collected to determine total cholesterol (TC), low-density lipoprotein cholesterol (LDL-cholesterol), and HDL-cholesterol, and triglycerides (TG) levels.

resultsThe prevalence of high TC, high LDL-cholesterol, low HDL-cholesterol, and high TG were 1.0%, 0.6%, 60.9%, and 13.7%, respectively. TC, LDL-cholesterol, and TG increased with age in females. Elevated TC was more common in females than in males. The prevalence of low HDL-cholesterol was 67.6% in males and 55.4% in females. Current smokers, those with less education, those who were overweight or obese, and those with large waist circumference were more likely to have low HDL-cholesterol (p<0.05). Multivariable regression showed that male gender showed an association with low HDL-cholesterol (OR 2.10, 95%CI 1.68-2.61), age ≥60 years (OR 0.80, 95% CI 0.64-0.99), BMI (BMI = 24-27.9, OR 1.27, 95%CI 1.04-1.54, p = 0.02 and BMI≥28, OR 1.56, 95%CI 1.10-2.20, p = 0.01) and enlarged waist circumference (OR 2.10, 95%CI 1.51-2.92). Non-alcohol drinker was associated with low HDL-cholesterol levels (OR 0.72, 95%CI 0.53-0.99, p = 0.04).

conclusionsThis study found that the prevalence of low HDL-cholesterol was 67.6% and 55.4% for males and females. Male gender, non-alcohol drinker, BMI and central obesity were important risk factors for low HDL-cholesterol in Chinese adults.

Indexed as

Rural PopulationAdultAlcohol DrinkingBlood PressureBody Mass IndexCardiovascular DiseasesChinaCholesterol, HDLCholesterol, LDLCross-Sectional StudiesDyslipidemiasFemaleHumansMaleMiddle AgedObesityCholesterol, HDLCholesterol, LDLTriglycerides

Identifiers

PMID26640891
PMCPMC4671591
OpenAlexW2193747488

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.