Evidence map›Paper›PMID 26640747›Full record

ArticleNanotechnology reviews2015

Nanotechnology for photodynamic therapy: a perspective from the Laboratory of Dr. Michael R. Hamblin in the Wellman Center for Photomedicine at Massachusetts General Hospital and Harvard Medical School.

Michael R Hamblin, Long Y Chiang, Shanmugamurthy Lakshmanan, Ying-Ying Huang, Maria Garcia-Diaz, Mahdi Karimi, Alessandra Nara de Souza Rastelli, Rakkiyappan Chandran

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanotechnology reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Carbon Dots in Photodynamic/Photothermal Antimicrobial Therapy.Nanomaterials (Basel, Switzerland) · 2024
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Toxicologic Concerns with Current Medical Nanoparticles.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Applications of Noble Metal-Based Nanoparticles in Medicine.International journal of molecular sciences · 2018
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Michael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom Street, Boston, MA 02114, USA; Department of Dermatology, Harvard Medical School, Boston, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA.
Long Y ChiangDepartment of Chemistry, University of Massachusetts, Lowell, MA, USA.
Shanmugamurthy LakshmananWellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom Street, Boston, MA 02114, USA; Department of Dermatology, Harvard Medical School, Boston, MA, USA.
Ying-Ying HuangWellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom Street, Boston, MA 02114, USA; Department of Dermatology, Harvard Medical School, Boston, MA, USA.
Maria Garcia-DiazDepartment of Pharmacy, University of Copenhagen, Denmark.
Mahdi KarimiIran University of Medical Science, Tehran, Iran.
Alessandra Nara de Souza RastelliAraraquara School of Dentistry-UNESP, SP, Brazil.
Rakkiyappan ChandranJoint School of Nanoscience and Nanoengineering, University of North Carolina, Greensboro, NC, USA.
Iran University of Medical Sciences · IRUniversidade Estadual Paulista (Unesp) · BRUniversity of Copenhagen · DKUniversity of Massachusetts Lowell · USUniversity of North Carolina at Greensboro · US

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
NIAID NIH HHS R01 AI050875
6 · The paper itself

Abstract

The research interests of the Hamblin Laboratory are broadly centered on the use of different kinds of light to treat many different diseases. Photodynamic therapy (PDT) uses the combination of dyes with visible light to produce reactive oxygen species and kill bacteria, cancer cells and destroy unwanted tissue. Likewise, UV light is also good at killing especially pathogens. By contrast, red or near-infrared light can have the opposite effect, to act to preserve tissue from dying and can stimulate healing and regeneration. In all these applications, nanotechnology is having an ever-growing impact. In PDT, self-assembled nano-drug carriers (micelles, liposomes, etc.) play a great role in solubilizing the photosensitizers, metal nanoparticles can carry out plasmon resonance enhancement, and fullerenes can act as photosensitizers, themselves. In the realm of healing, single-walled carbon nanotubes can be electrofocused to produce nano-electonic biomedical devices, and nanomaterials will play a great role in restorative dentistry.

Indexed as

Hamblin Laboratorynanotechnologyphotodynamic therapy

Identifiers

PMID26640747
PMCPMC4666539
OpenAlexW2419058078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.