Evidence map›Paper›PMID 26640653›Full record

ArticleInterface focus2015

Neuronal boost to evolutionary dynamics.

Harold P de Vladar, Eörs Szathmáry

Abstract read
In one paragraph

Article in Interface focus, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Harold P de VladarCenter for the Conceptual Foundations of Science , Parmenides Foundation , Kirchplatz 1, Pullach 82049 , Germany.
Eörs SzathmáryCenter for the Conceptual Foundations of Science , Parmenides Foundation , Kirchplatz 1, Pullach 82049 , Germany ; Institute of Biology , Eötvös University , Pázmány Péter sétány 1/C, Budapest 1117 , Hungary ; TMTA-ELTE Theoretical Biology and Evolutionary Ecology Research Group , Pázmány Péter sétány 1/C, Budapest 1117 , Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Standard evolutionary dynamics is limited by the constraints of the genetic system. A central message of evolutionary neurodynamics is that evolutionary dynamics in the brain can happen in a neuronal niche in real time, despite the fact that neurons do not reproduce. We show that Hebbian learning and structural synaptic plasticity broaden the capacity for informational replication and guided variability provided a neuronally plausible mechanism of replication is in place. The synergy between learning and selection is more efficient than the equivalent search by mutation selection. We also consider asymmetric landscapes and show that the learning weights become correlated with the fitness gradient. That is, the neuronal complexes learn the local properties of the fitness landscape, resulting in the generation of variability directed towards the direction of fitness increase, as if mutations in a genetic pool were drawn such that they would increase reproductive success. Evolution might thus be more efficient within evolved brains than among organisms out in the wild.

Indexed as

Darwinian neurodynamicsevolutionary dynamicsHebbian learningsynaptic plasticity

Identifiers

PMID26640653
PMCPMC4633863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.