ReviewAdvances in urology2015
A Review of the Literature on Primary Leiomyosarcoma of the Prostate Gland.
Review in Advances in urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- Two faces of malignancy in one prostate: A rare coexistence of adenocarcinoma and leiomyosarcoma.Urology case reports · 2026Article
- Very rare synchronous malignant tumors of the Prostate: Leiomyosarcoma and adenocarcinoma - A case report and literature review.Urology case reports · 2025Article
- Leiomyosarcoma of lower urinary tract: Literature review.Central European journal of urology · 2025Review
- Leiomyosarcoma of the prostate: a novel approach to treatment-case report and review of the literature.Journal of surgical case reports · 2024Article
- Long-term disease control after upfront chemotherapy and surgery in a patient with primary prostate leiomyosarcoma.IJU case reports · 2022Article
- Can pelvic radiotherapy induce a leiomyosarcoma of the prostate? (A case report).The Pan African medical journal · 2022Article
- Incidental findings in and around the prostate on prostate MRI: a pictorial review.Insights into imaging · 2021Review
- Prostatic leiomyosarcoma in a dog treated using a multimodal approach.Journal of veterinary internal medicine · 2021Article
- Prostate sarcomas: A radiological mimic for benign prostatic hyperplasia.Urology case reports · 2020Article
- Promising effects of pazopanib with radiation on an advanced prostate leiomyosarcoma after failure of systemic chemotherapy.The Kaohsiung journal of medical sciences · 2019Article
- Presentation of a Rare Malignancy: Leiomyosarcoma of the Prostate.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2019Article
- Review
- Leiomyosarcoma of prostate: Case report and literature review.Urology case reports · 2018Article
- Leiomyosarcoma of the Prostate: Report of Two Cases and Review of the Literature.Case reports in oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary leiomyosarcoma of the prostate (PLSOP) is rare, with less than 200 cases reported so far. PLSOPs present with lower urinary tract symptoms, haematuria, and perineal pain; may or may not be associated with a history of previous treatment for adenocarcinoma of prostate by means of radiotherapy and or hormonal treatment; may afflict children and adult male. Examination may reveal benign enlarged prostate and hard enlarged mass. PLSOPs may be diagnosed by histological examination findings of spindle-shaped carcinoma cells in prostate specimens. Immunohistochemical staining tends to be positive for vimentin, CD44, smooth muscle actin, and calponin, focally positive for desmin, and at times positive for keratin. They stain negatively for PSA, S-100, CD34, CD117, and cytokeratin. Cytogenetic study on primary leiomyosarcoma of the prostate gland may show clonal chromosomal rearrangement involving Chromosomes 2, 3, 9, 11, and 19. On the whole the prognosis is poor. Surgery with or without chemotherapy would appear to be the mainstay of treatment for PLSOPs that are operable, but generally there is no consensus opinion on the best therapeutic approach. Most cases of PLSOPs are diagnosed in an advanced stage of the disease. A global multicenter trial is required to find therapies that would improve the prognosis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.