Evidence map›Paper›PMID 26640374›Full record

ReviewNanotechnology, science and applications2015

Nanotechnology-based inhalation treatments for lung cancer: state of the art.

Javed Ahmad, Sohail Akhter, Md Rizwanullah, Saima Amin, Mahfoozur Rahman, Mohammad Zaki Ahmad, Moshahid Alam Rizvi, Mohammad A Kamal, Farhan Jalees Ahmad

Open access · goldAbstract readReview
In one paragraph

Review in Nanotechnology, science and applications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 169 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Inhalable nanoparticle-based drug delivery system for non-small cell lung cancer therapy: promises and challenges.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Drug-loaded polymer-coated silver nanoparticles for lung cancer theranostics.Medical oncology (Northwood, London, England) · 2024
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Aerosol pulmonary immune engineering.Advanced drug delivery reviews · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Javed AhmadDepartment of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India.
Sohail AkhterNanomedicine Research Lab, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India ; Centre de Biophysique Moléculaire(CBM)-CNRS UPR4301, University of Orléans, Orléans Cedex 2, France.
Md RizwanullahDepartment of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India.
Saima AminDepartment of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India.
Mahfoozur RahmanDepartment of Pharmaceutics, Abhilashi College of Pharmacy, Mandi, HP, India.
Mohammad Zaki AhmadDepartment of Pharmaceutics, College of Pharmacy, Najran University, Saudi Arabia.
Moshahid Alam RizviDepartment of Biosciences, Jamia Millia Islamia, New Delhi, India.
Mohammad A KamalMetabolomics and Enzymology Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
Farhan Jalees AhmadDepartment of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India ; Nanomedicine Research Lab, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India.
Jamia Hamdard · INAmerican Pharmacists Association · USCentre de Biophysique Moléculaire · FRJamia Millia Islamia · INKing Abdulaziz University · SANajran University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considering the challenges associated with conventional chemotherapy, targeted and local delivery of chemotherapeutics via nanoparticle (NP) carriers to the lungs is an emerging area of interest. Recent studies and growing clinical application in cancer nanotechnology showed the huge potential of NPs as drug carriers in cancer therapy, including in lung carcinoma for diagnosis, imaging, and theranostics. Researchers have confirmed that nanotechnology-based inhalation chemotherapy is viable and more effective than conventional chemotherapy, with lesser side effects. Recently, many nanocarriers have been investigated, including liposomes, polymeric micelles, polymeric NPs, solid lipid NPs, and inorganic NPs for inhalation treatments of lung cancer. Yet, the toxicity of such nanomaterials to the lungs tissues and further distribution to other organs due to systemic absorption on inhalation delivery is a debatable concern. Here, prospect of NPs-based local lung cancer targeting through inhalation route as well as its associated challenges are discussed.

Indexed as

drug targetinginhalational chemotherapylung cancernanoparticlesnanotoxicity

Identifiers

PMID26640374
PMCPMC4657804
OpenAlexW2193867915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.