Evidence map›Paper›PMID 26640365›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2015

Significance of the disc damage likelihood scale objectively measured by a non-mydriatic fundus camera in preperimetric glaucoma.

Milena Pahlitzsch, Necip Torun, Carl Erb, Jeanette Bruenner, Anna Karina B Maier, Johannes Gonnermann, Eckart Bertelmann, Matthias K J Klamann

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Spotlight on the Disc-Damage Likelihood Scale (DDLS).Clinical ophthalmology (Auckland, N.Z.) · 2021
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Milena PahlitzschDepartment of Ophthalmology, University Medicine Charité, Campus Virchow Clinic, Berlin, Germany.
Necip TorunDepartment of Ophthalmology, University Medicine Charité, Campus Virchow Clinic, Berlin, Germany.
Carl ErbAugenklinik am Wittenbergplatz, Berlin, Germany.
Jeanette BruennerDepartment of Ophthalmology, University Medicine Charité, Campus Virchow Clinic, Berlin, Germany.
Anna Karina B MaierDepartment of Ophthalmology, University Medicine Charité, Campus Virchow Clinic, Berlin, Germany.
Johannes GonnermannDepartment of Ophthalmology, University Medicine Charité, Campus Virchow Clinic, Berlin, Germany.
Eckart BertelmannDepartment of Ophthalmology, University Medicine Charité, Campus Virchow Clinic, Berlin, Germany.
Matthias K J KlamannDepartment of Ophthalmology, University Medicine Charité, Campus Virchow Clinic, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the correlation between the disc damage likelihood scale (DDLS) objectively measured by a non-mydriatic fundus camera, Heidelberg Retina Tomograph 3, and optic coherence tomography in preperimetric glaucoma.

methodsOne-hundred-twenty-five patients with preperimetric primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (n=30) were included (mean age 58.9±15.9 years). All three devices graded the optic disc topography: Diagnosis 1 was defined as "outside normal limits", while Diagnosis 2 as "borderline or outside normal limits".

resultsFor Diagnosis 1, a significant correlation was shown between DDLS and Moorfields regression analysis (P=0.022), and for Diagnosis 2 with glaucoma probability score analysis (P=0.024), in POAG. In pseudoexfoliation glaucoma, DDLS did not correlate significantly with Heidelberg Retina Tomograph 3 and optic coherence tomography. Regarding the area under the curve the highest predictive power was demonstrated by the objective DDLS (0.513-0.824) compared to Burk (0.239-0.343) and Mikelberg (0.093-0.270) coefficients.

conclusionsThe DDLS showed a significant correlation to the Moorfields regression analysis in preperimetric POAG. The objective DDLS showed the highest predictive power and thus is an additive tool in diagnosing preperimetric glaucoma.

Indexed as

DDLSHeidelberg Retina Tomographoptic coherence tomographypreperimetric glaucomastereophotography

Identifiers

PMID26640365
PMCPMC4662372
OpenAlexW2179290232

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.