ArticleWorld journal of gastroenterology2015
Gastric cancer risk in relation to tobacco use and alcohol drinking in Kerala, India--Karunagappally cohort study.
Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Gastroesophageal disease risk and inhalational exposure a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Quercetin inhibits gastric cancer cell proliferation and migration and is associated with the suppression of the IDO1-Kynurenine-AhR axis.BMC cancer · 2025Article
- The global burden of stomach cancer and its risk factors from 1990 to 2021: findings from the Global Burden of Disease Study 2021.BMC public health · 2025Article
- Sequence Variation in X-ray Cross Complimenting (XRCC4, XRCC5, XRCC6 and XRCC7) Genes and the Risk of Gastrointestinal Cancer in South-Western Maharashtra: A Hospital Based Case-Control Study.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Environmental factors inducing gastric cancer: insights into risk and prevention strategies.Discover oncology · 2025Review
- Precancerous pathways to gastric cancer: a review of experimental animal models recapitulating the correa cascade.Frontiers in cell and developmental biology · 2025Review
- Clinical presentation and treatment outcomes of gastric adenocarcinoma patients: a retrospective study from Ain Shams Clinical Oncology Department.Ecancermedicalscience · 2025Article
- Long-term assessment of Helicobacter pylori cagA EPIYA motif changes and pathology outcomes in gastric biopsies of dyspeptic patients: 10-year follow-up.BMC gastroenterology · 2024Article
- Elucidating gastric cancer mechanisms and therapeutic potential of Adociaquinone A targeting EGFR: A genomic analysis and Computer Aided Drug Design (CADD) approach.Journal of cellular and molecular medicine · 2024Article
- A prospective cohort study on the association between waterpipe tobacco smoking and gastric cancer mortality in Northern Vietnam.BMC cancer · 2022Article
- Analysis of Collagen type X alpha 1 (COL10A1) expression and prognostic significance in gastric cancer based on bioinformatics.Bioengineered · 2021Article
- Sex as an effect modifier in the association between alcohol intake and gastric cancer risk.World journal of gastrointestinal oncology · 2021Article
- Lifestyle factors and long-term survival of gastric cancer patients: A large bidirectional cohort study from China.World journal of gastroenterology · 2020Article
- Thyroid nodule prevalence among women in areas of high natural background radiation, Karunagappally, Kerala, India.Endocrine · 2020Article
- Association between alcohol consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies.Oncotarget · 2017Article
- Alcohol consumption and gastric cancer risk: a meta-analysis of prospective cohort studies.Oncotarget · 2017Article
- Prevalence of overweight and obesity and some associated factors among adult residents of northeast China: a cross-sectional study.BMJ open · 2016Article
- Types of Obesity and Its Association with the Clustering of Cardiovascular Disease Risk Factors in Jilin Province of China.International journal of environmental research and public health · 2016Article
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Authors and funding
6 authors at 1 institution in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the risk of gastric cancer (GC) in relation to tobacco use and alcohol drinking in the Karunagappally cohort in Kerala, South India.
methodsThis study examined the association of tobacco use and alcohol drinking with GC incidence among 65553 men aged 30-84 in the Karunagappally cohort. During the period from 1990-2009, 116 GC cases in the cohort were identified as incident cancers. These cases were identified from the population-based cancer registry. Information regarding risk factors such as socioeconomic factors and tobacco and alcohol habits of cohort members were collected from the database of the baseline survey conducted during 1990-1997. The relative risks (RRs) and the corresponding 95% confidence intervals (95%CIs) for tobacco use were obtained from Poisson regression analysis of grouped survival data, considering age, follow-up period, occupation and education.
resultsBidi smoking was associated with GC risk (P = 0.042). The RR comparing current versus never smokers was 1.6 (95%CI: 1.0-2.5). GC risk was associated with the number of bidis smoked daily (P = 0.012) and with the duration of bidi smoking (P = 0.036). Those who started bidi smoking at younger ages were at an elevated GC risk; the RRs for those starting bidi smoking under the age of 18 and ages 18-22 were 2.0 (95%CI: 1.0-3.9) and 1.8 (95%CI: 1.1-2.9), respectively, when their risks were compared with lifetime non-smokers of bidis. Bidi smoking increased the risk of GC among never cigarette smokers more evidently (RR = 2.2; 95%CI: 1.3-4.0). GC risk increased with the cumulative amount of bidi smoking, which was calculated as the number of bidis smoked per day x years of smoking (bidi-year; P = 0.017). Cigarette smoking, tobacco chewing or alcohol drinking was not significantly associated with GC risk.
conclusionAmong a male cohort in South India, gastric cancer risk increased with the number and duration of bidi smoking.
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