ArticleTetrahedron2015
Recent Advances in the C-H-Functionalization of the Distal Positions in Pyridines and Quinolines.
Article in Tetrahedron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- C-H Activation of Pyridines by Boryl Pincer Complexes: Elucidation of Boryl-Directed C-H Oxidative Addition to Ir and Discovery of Transition Metal-Assisted Reductive Elimination from Boron at Rh.Journal of the American Chemical Society · 2024Article
- Electrochemical meta-C-H sulfonylation of pyridines with nucleophilic sulfinates.Nature communications · 2024Article
- Tunably strained metallacycles enable modular differentiation of aza-arene C-H bonds.Nature communications · 2023Article
- Article
- Rhodium-Promoted C-H Bond Activation of Quinoline, Methylquinolines, and Related Mono-Substituted Quinolines.Organometallics · 2022Article
- A directive Ni catalyst overrides conventional site selectivity in pyridine C-H alkenylation.Nature chemistry · 2021Article
- Photoinduced C(spChemical science · 2021Article
- Regioselective Functionalization of Quinolines through C-H Activation: A Comprehensive Review.Molecules (Basel, Switzerland) · 2021Review
- Nucleophilic C-H Etherification of Heteroarenes Enabled by Base-Catalyzed Halogen Transfer.Journal of the American Chemical Society · 2021Article
- Investigations of the Optical and Thermal Properties of the Pyrazoloquinoline Derivatives and Their Application for OLED Design.Polymers · 2020Article
- Base-catalyzed aryl halide isomerization enables the 4-selective substitution of 3-bromopyridines.Chemical science · 2020Article
- Highly Stereoselective and Catalytic Desulfitative C-O and C-I Dienylation with Sulfolenes: the Importance of Basic Additives.Tetrahedron · 2019Article
- Perfluoroalkylative pyridylation of alkenesChemical science · 2019Article
- Organoboron chemistry comes to light: recent advances in photoinduced synthetic approaches to organoboron compounds.Tetrahedron · 2019Article
- An efficient nickel/silver co-catalyzed remote C-H amination of 8-aminoquinolines with azodicarboxylates at room temperature.RSC advances · 2018Article
- Antiviral Activity of Novel Quinoline Derivatives against Dengue Virus Serotype 2.Molecules (Basel, Switzerland) · 2018Article
- DABCO- and DBU-promoted one-pot reaction ofBeilstein journal of organic chemistry · 2018Article
- Organocatalytic Synthesis of Methylene-Bridged N-Heterobiaryls.Organic letters · 2016Article
- Ruthenium-Catalyzed C-H Arylation of Diverse Aryl Carboxylic Acids with Aryl and Heteroaryl Halides.Organic letters · 2016Article
- Mechanistic insights into the potassium tert-butoxide-mediated synthesis of N-heterobiaryls.Chemical communications (Cambridge, England) · 2016Article
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2 authors.
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Abstract
This review summarizes recent developments in the C-H-functionalization of the distal positions of pyridines, quinolines and related azaheterocycles. While the functionalization of the C2 position has been known for a long time and is facilitated by the proximity to N1, regioselective reactions in the distal positions are more difficult to achieve and have only emerged in the last decade. Recent advances in the transition metal-catalyzed distal C-H-functionalization of these synthetically-important azaheterocycles are discussed in detail, with the focus on the scope, site-selectivity and mechanistic aspects of the reactions.
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