ArticleResuscitation2016
Regional incidence and outcome of out-of-hospital cardiac arrest associated with overdose.
Article in Resuscitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Naloxone and Clinical Outcomes in Suspected Opioid-Associated Out-of-Hospital Cardiac Arrests.JAMA network open · 2026Article
- Barriers to bystander interventions in suspected opioid-associated out-of-hospital cardiac arrests: A multiple methods study of 9-1-1 calls.Resuscitation · 2025Article
- Impact of the COVID-19 pandemic on poisoning induced out of hospital cardiac arrest in South Korea retrospective observational study.Scientific reports · 2025Observational
- Evaluating the accuracy of surrogate markers for identifying opioid-associated out-of-hospital cardiac arrests.Resuscitation · 2025Article
- The outcome of out-of-hospital cardiac arrest based on the etiology of cardiac arrest; A scoping review.PloS one · 2025Article
- Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California.JAMA network open · 2024Article
- Trends in presumed drug overdose out-of-hospital cardiac arrests in San Francisco, 2015-2023.Resuscitation · 2024Article
- Cardiac Arrest Following Drug Overdose in the United States: An Analysis of the Cardiac Arrest Registry to Enhance Survival.Journal of the American Heart Association · 2024Article
- Nationwide population-based study of poisoning-induced out-of-hospital cardiac arrest in South Korea.BMJ open · 2022Article
- Severe cerebral edema in substance-related cardiac arrest patients.Resuscitation · 2022Article
- Phenotyping Cardiac Arrest: Bench and Bedside Characterization of Brain and Heart Injury Based on Etiology.Critical care medicine · 2018Observational
- Poisoning-induced Out-of-Hospital Cardiac Arrest and Outcomes according to Poison Agent.Journal of Korean medical science · 2017Article
- Out-of-hospital cardiac arrest survival in drug-related versus cardiac causes in Ontario: A retrospective cohort study.PloS one · 2017Article
- The benefits of youth are lost on the young cardiac arrest patient.F1000Research · 2017Review
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThe frequency of lethal overdose due to prescription and non-prescription drugs is increasing in North America. The aim of this study was to estimate overall and regional variation in incidence and outcomes of out-of-hospital cardiac arrest due to overdose across North America.
methodsWe conducted a retrospective cohort study using case data for the period 2006-2010 from the Resuscitation Outcomes Consortium, a clinical research network with 10 regional clinical centers in United States and Canada. Cases of out-of-hospital cardiac arrest due to drug overdose were identified through review of data derived from prehospital clinical records. We calculated incidence of out-of-hospital cardiac arrest due to overdose per 100,000 person-years and proportion of the same among all out-of-hospital cardiac arrests. We analyzed the association between overdose cardiac arrest etiology and resuscitation outcomes.
resultsIncluded were 56,272 cases, of which 1351 were due to overdose. Regional incidence of out-of-hospital cardiac arrest due to overdose varied between 0.5 and 2.7 per 100,000 person years (p<0.001), and proportion of the same among all treated out-of-hospital cardiac arrests ranged from 0.8% to 4.0%. Overdose cases were younger, less likely to be witnessed, and less likely to present with a shockable rhythm. Compared to non-overdose, overdose was directly associated with return of spontaneous circulation (OR: 1.55; 95% CI: 1.35-1.78) and survival (OR: 2.14; 95% CI: 1.72-2.65).
conclusionsOverdose made up 2.4% of all out-of-hospital cardiac arrest, although incidence varied up to 5-fold across regions. Overdose cases were more likely to survive than non-overdose cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.