Evidence map›Paper›PMID 26639673›Full record

ArticleScientific reports2015

The Potential of High Resolution Magnetic Resonance Microscopy in the Pathologic Analysis of Resected Breast and Lymph Tissue.

Brittany Z Dashevsky, Timothy D'Alfonso, Elizabeth J Sutton, Ashley Giambrone, Eric Aronowitz, Elizabeth A Morris, Krishna Juluru, Douglas J Ballon

Abstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Intraoperative imaging in pathology-assisted surgery.Nature biomedical engineering · 2022
    Review
  5. Review
  6. Assessing Histology Structures byFrontiers in oncology · 2021
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review of quantitative multiscale imaging of breast cancer.Journal of medical imaging (Bellingham, Wash.) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Brittany Z DashevskyDepartment of Radiology, Weill Cornell Medical College, Cornell University, New York, NY.
Timothy D'AlfonsoDepartment of Pathology, Weill Cornell Medical College, Cornell University, New York, NY.
Elizabeth J SuttonDepartment of Radiology, Memorial Sloan, Kettering Cancer Center, New York, NY.
Ashley GiambroneDepartment of Healthcare Policy, Weill Cornell Medical College, Cornell University, New York, NY.
Eric AronowitzDepartment of Radiology, Weill Cornell Medical College, Cornell University, New York, NY.
Elizabeth A MorrisDepartment of Pathology, Weill Cornell Medical College, Cornell University, New York, NY.
Krishna JuluruDepartment of Radiology, Weill Cornell Medical College, Cornell University, New York, NY.
Douglas J BallonDepartment of Physics, Weill Cornell Medical College, Cornell University, New York, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathologic evaluation of breast specimens requires a fixation and staining procedure of at least 12 hours duration, delaying diagnosis and post-operative planning. Here we introduce an MRI technique with a custom-designed radiofrequency resonator for imaging breast and lymph tissue with sufficient spatial resolution and speed to guide pathologic interpretation and offer value in clinical decision making. In this study, we demonstrate the ability to image breast and lymphatic tissue using 7.0 Tesla MRI, achieving a spatial resolution of 59 × 59 × 94 μm(3) with a signal-to-noise ratio of 15-20, in an imaging time of 56 to 70 minutes. These are the first MR images to reveal characteristic pathologic features of both benign and malignant breast and lymph tissue, some of which were discernible by blinded pathologists who had no prior training in high resolution MRI interpretation.

Indexed as

BreastDiagnostic ImagingFemaleHumansLymph NodesMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMicroscopySurveys and Questionnaires

Identifiers

PMID26639673
PMCPMC4671009

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.