ArticleAnalytical chemistry2016
Carbon Nanotubes Grown on Metal Microelectrodes for the Detection of Dopamine.
Article in Analytical chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 131 citations in OpenAlex.
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- Innovating carbon-based electrodes for direct neurochemical detection along the brain-immune axis.Current opinion in electrochemistry · 2025Article
- Glassy Carbon Fiber-like Multielectrode Arrays for Neurochemical Sensing and Electrophysiology Recording.Advanced materials technologies · 2025Article
- Carbon microelectrodes for the measurement of neurotransmitters with fast-scan cyclic voltammetry: methodology and applications.Frontiers in bioengineering and biotechnology · 2025Review
- Preparation and characterization of polydopamine andRSC advances · 2024Article
- Batch Fabrication of Microelectrode Arrays with Glassy Carbon Microelectrodes and Interconnections for Neurochemical Sensing: Promises and Challenges.Micromachines · 2024Article
- Carbon nanospikes have improved sensitivity and antifouling properties for adenosine, hydrogen peroxide, and histamine.Analytical and bioanalytical chemistry · 2023Article
- Sensing and Stimulation Applications of Carbon Nanomaterials in Implantable Brain-Computer Interface.International journal of molecular sciences · 2023Review
- Carbon microelectrodes with customized shapes for neurotransmitter detection: A review.Analytica chimica acta · 2022Review
- Flexible Glassy Carbon Multielectrode Array forBiosensors · 2022Article
- Novel Amperometric Biosensor Based on Tyrosinase/Chitosan Nanoparticles for Sensitive and Interference-Free Detection of Total Catecholamine.Biosensors · 2022Article
- The First Silver-Based Plasmonic Nanomaterial for Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy with Magnetic Properties.Molecules (Basel, Switzerland) · 2022Article
- Microneedle-based nanoporous gold electrochemical sensor for real-time catecholamine detection.Mikrochimica acta · 2022Article
- Article
- Porous Carbon Nanofiber-Modified Carbon Fiber Microelectrodes for Dopamine Detection.ACS applied nano materials · 2022Article
- 3D fuzzy graphene microelectrode array for dopamine sensing at sub-cellular spatial resolution.Biosensors & bioelectronics · 2021Article
- Multiplexing neurochemical detection with carbon fiber multielectrode arrays using fast-scan cyclic voltammetry.Analytical and bioanalytical chemistry · 2021Article
- Vesicle Impact Electrochemical Cytometry to Determine Carbon Nanotube-Induced Fusion of Intracellular Vesicles.Analytical chemistry · 2021Article
- Electrode Materials for Chronic Electrical Microstimulation.Advanced healthcare materials · 2021Review
- Amine-functionalized carbon-fiber microelectrodes for enhanced ATP detection with fast-scan cyclic voltammetry.Analytical methods : advancing methods and applications · 2021Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Microelectrodes modified with carbon nanotubes (CNTs) are useful for the detection of neurotransmitters because the CNTs enhance sensitivity and have electrocatalytic effects. CNTs can be grown on carbon fiber microelectrodes (CFMEs) but the intrinsic electrochemical activity of carbon fibers makes evaluating the effect of CNT enhancement difficult. Metal wires are highly conductive and many metals have no intrinsic electrochemical activity for dopamine, so we investigated CNTs grown on metal wires as microelectrodes for neurotransmitter detection. In this work, we successfully grew CNTs on niobium substrates for the first time. Instead of planar metal surfaces, metal wires with a diameter of only 25 μm were used as CNT substrates; these have potential in tissue applications due to their minimal tissue damage and high spatial resolution. Scanning electron microscopy shows that aligned CNTs are grown on metal wires after chemical vapor deposition. By use of fast-scan cyclic voltammetry, CNT-coated niobium (CNT-Nb) microelectrodes exhibit higher sensitivity and lower ΔEp value compared to CNTs grown on carbon fibers or other metal wires. The limit of detection for dopamine at CNT-Nb microelectrodes is 11 ± 1 nM, which is approximately 2-fold lower than that of bare CFMEs. Adsorption processes were modeled with a Langmuir isotherm, and detection of other neurochemicals was also characterized, including ascorbic acid, 3,4-dihydroxyphenylacetic acid, serotonin, adenosine, and histamine. CNT-Nb microelectrodes were used to monitor stimulated dopamine release in anesthetized rats with high sensitivity. This study demonstrates that CNT-grown metal microelectrodes, especially CNTs grown on Nb microelectrodes, are useful for monitoring neurotransmitters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.