ArticleAddiction (Abingdon, England)2016
Daily alcohol use as an independent risk factor for HIV seroconversion among people who inject drugs.
Article in Addiction (Abingdon, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users.The Cochrane database of systematic reviews · 2018Pooled it
- HealthCall delivered via smartphone to reduce co-occurring drug and alcohol use in HIV-infected adults: A randomized pilot trial.Journal of substance abuse treatment · 2017Trial
- Prevalence and Correlates of Heavy Alcohol use among People Living with HIV who use Unregulated Drugs in Vancouver, Canada.AIDS and behavior · 2024Article
- Negative Consequences of Alcohol Use among People Living with HIV.Substance use & misuse · 2021Article
- Antiretroviral Therapy and Alcohol Interactions: X-raying Testicular and Seminal Parameters Under the HAART Era.European journal of drug metabolism and pharmacokinetics · 2018Review
- A Cohort Approach to Real-Time Detection of Acute HIV Infections Among People Who Inject Drugs in St. Petersburg, Russia.AIDS research and human retroviruses · 2018Article
- Prevalence of Heavy Alcohol Use Among People Receiving Methadone Following Change to Methadose.Substance use & misuse · 2018Article
- Task-shifting alcohol interventions for HIV+ persons in Kenya: a cost-benefit analysis.BMC health services research · 2017Article
- Elevated risk of incarceration among street-involved youth who initiate drug dealing.Harm reduction journal · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
aimsTo estimate the relationship between daily alcohol use and HIV seroconversion among people who inject drugs (PWID) in a Canadian setting. DESIGN AND
settingData from an open prospective cohort study of PWID in Vancouver, Canada, recruited via snowball sampling and street outreach between May 1996 and November 2013. An interviewer-administered questionnaire including standardized behavioural assessment and HIV antibody testing were conducted semi-annually. Baseline HIV-seronegative participants completing ≥ 1 follow-up visits were eligible for the present analysis.
participantsA total of 1683 eligible participants, were followed for a median of 79.8 [interquartile range (IQR) = 33.3-119.1] months. MEASUREMENTS: The primary end-point was time to HIV seroconversion, with the date of HIV seroconversion estimated as the mid-point between the last negative and the first positive antibody test results. The primary explanatory variable was self-reported daily alcohol use in the previous 6 months assessed semiannually. Other covariates considered included demographic, behavioural, social/structural and environmental risk factors for HIV infection among PWID (e.g. daily cocaine injection, methadone use, etc.).
findingsOf 1683 PWID, there were 176 HIV seroconversions during follow-up with an incidence density of 1.5 [95% confidence interval (CI) = 1.3-1.7] cases per 100 person-years. At baseline, 339 (20.1%) consumed alcohol at least daily in the previous 6 months. In multivariable extended Cox regression analyses, daily alcohol use remained associated independently with HIV seroconversion (adjusted hazard ratio: 1.48; 95% CI = 1.00-2.17).
conclusionsDaily alcohol use appears to be an independent risk factor for HIV seroconversion among our cohort of PWID.
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