Evidence map›Paper›PMID 26638191›Full record

ArticleHepatology (Baltimore, Md.)2016

HEDGEHOG Signal in hepatocytes mediates macrophage recruitment: A new mechanism and potential therapeutic target for fatty liver disease.

Ekihiro Seki

Abstract readEditorialComment
In one paragraph

Article in Hepatology (Baltimore, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Ekihiro SekiDivision of Gastroenterology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.

Funding

Yeast Genetics and Stress Response Genes-BiomedicalP42ES010337 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TUKEY, ROBERT H · 2000 to 2022
$69.8M
LPS binding to TLR4 regulates hepatic stellate cell activation and fibrosisR01DK085252 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EKIHIRO SEKI · 2011 to 2026
$4.8M
Synergistic Actions By Multiple Toll-Like Receptors in Alcoholic Liver DiseaseR01AA020172 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEKI, EKIHIRO · 2010 to 2014
$1.8M
NIAAA NIH HHS R01 AA020172NIDDK NIH HHS R01 DK085252NIEHS NIH HHS P42 ES010337
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diet, High-FatAnilidesAnimalsHedgehog ProteinsInflammationNon-alcoholic Fatty Liver DiseasePyridinesSignal TransductionAnilidesHedgehog ProteinsPyridines

Identifiers

PMID26638191
PMCPMC4805480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.