Evidence map›Paper›PMID 26638030›Full record

ReviewCurrent opinion in microbiology2016

Yersinia versus host immunity: how a pathogen evades or triggers a protective response.

Lawton K Chung, James B Bliska

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
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  9. Review
  10. Article
  11. Distinct Mechanisms of Type 3 Secretion System Recognition Control LTBbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Engineering a HyperstableJournal of the American Chemical Society · 2022
    Article
  16. Review
  17. β-hydroxybutyrate impairs monocyte functionFrontiers in veterinary science · 2022
    Article
  18. Review
  19. Review
  20. The pyrin inflammasome in host-microbe interactions.Current opinion in microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lawton K ChungDepartment of Molecular Genetics and Microbiology and Center for Infectious Diseases, Stony Brook University, Stony Brook, NY 11794-5120, United States.
James B BliskaDepartment of Molecular Genetics and Microbiology and Center for Infectious Diseases, Stony Brook University, Stony Brook, NY 11794-5120, United States. Electronic address: james.bliska@stonybrook.edu.

Funding

Regulation of host innate and adaptive immunity by bacterial type III effectorsR01AI099222 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI BLISKA, JAMES B · 2012 to 2025
$5.9M
MOLECULAR AND CELL BIOLOGY OF INFECTIOUS DISEASEST32AI007539 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI KONOPKA, JAMES B · 1998 to 2023
$3.6M
Regulation of caspase-1 activation by IQGAP1 during bacterial infectionF31AI118220 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI CHUNG, LAWTON K · 2015 to 2016
$46k
NIAID NIH HHS F31 AI118220NIAID NIH HHS F31AI118220NIAID NIH HHS R01 AI099222NIAID NIH HHS R01AI099222NIAID NIH HHS T32 AI007539NIAID NIH HHS T32AI007539
6 · The paper itself

Abstract

The human pathogenic Yersinia species cause diseases that represent a significant source of morbidity and mortality. Despite this, specific mechanisms underlying Yersinia pathogenesis and protective host responses remain poorly understood. Recent studies have shown that Yersinia disrupt cell death pathways, perturb inflammatory processes and exploit immune cells to promote disease. The ensuing host responses following Yersinia infection include coordination of innate and adaptive immune responses in an attempt to control bacterial replication. Here, we highlight current advances in our understanding of the interactions between the pathogenic yersiniae and host cells, as well as the protective host responses mobilized to counteract these pathogens. Together, these studies enhance our understanding of Yersinia pathogenesis and highlight the ongoing battle between host and microbe.

Indexed as

Immune EvasionAdaptive ImmunityAnimalsCell DeathHumansImmunity, InnateLungSignal TransductionYersiniaYersinia InfectionsYersinia pestis

Identifiers

PMID26638030
PMCPMC4755919

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.