ArticleClinical oral investigations2016
Effect of gaseous ozone on Enterococcus faecalis biofilm-an in vitro study.
Article in Clinical oral investigations, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 50 citations in OpenAlex.
- The Gaseous Ozone Therapy as a Promising Antiseptic Adjuvant of Periodontal Treatment: A Randomized Controlled Clinical Trial.International journal of environmental research and public health · 2022Trial
- Comparison of ozone gas and sodium hypochlorite/chlorhexidine two-visit disinfection protocols in treating apical periodontitis: a randomized controlled clinical trial.Clinical oral investigations · 2017Trial
- Targeting Oral Biofilms: Comparative In Vitro Evaluation of Commercial Dental Antiseptics Against Clinical and Reference Microbial Strains.International journal of molecular sciences · 2026Article
- In Vitro Antiviral and Virucidal Activity of Ozone against Feline Calicivirus.Animals : an open access journal from MDPI · 2024Article
- Potential Clinical Applications of Ozone Therapy in Dental Specialties-A Literature Review, Supported by Own Observations.International journal of environmental research and public health · 2023Review
- Disinfecting Action of Gaseous Ozone on OXA-48-ProducingInternational journal of environmental research and public health · 2022Article
- Application of Non-Thermal Plasma to Fungal Resources.Journal of fungi (Basel, Switzerland) · 2022Review
- The antimicrobial effect of different ozone protocols applied in severe curved canals contaminated with Enterococcus faecalis: ex vivo study.Odontology · 2021Article
- Cytotoxicity assessment of different doses of ozonated water on dental pulp cells.BMC oral health · 2021Article
- Ozone ultrafine bubble water induces the cellular signaling involved in oxidative stress responses in human periodontal ligament fibroblasts.Science and technology of advanced materials · 2019Article
- Effects of Diode Laser, Gaseous Ozone, and Medical Dressings onBioMed research international · 2017Article
- Efficiency of gaseous ozone in reducing the development of dry socket following surgical third molar extraction.European journal of dentistryArticle
- Anti-microbial efficiency of gaseous ozone's combined use with fluoride and chlorhexidine on time-related oral biofilm: anMedical gas researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to evaluate the antimicrobial effect of gaseous ozone compared to conventional methods against Enterococcus faecalis. MATERIALS AND
methodsOne hundred twenty-five teeth were infected by E. faecalis and were incubated for 72 h to form biofilm. Teeth were distributed among five groups. In the first group, ozone was used; in the second group, teeth were rinsed with 20 % ethylenediaminetetraacetic acid (EDTA); in the third group, with 3 % sodium hypochlorite (NaOCl). Group 4 combined 20 % EDTA with ozone. NaOCl and ozone were combined in group 5. After treatment, the samples with paper points were taken, followed by dentin samples taken with K-file, and cultured for 24 h. Then bacterial colonies were counted.
resultsAll treatments reduced significantly (p < 0.05) the bacteria. Paper points' samples showed 85.38 % reduction after ozone. The highest reduction was observed in NaOCl group (99.98 %). EDTA reduced bacteria by 80.64 %. Combination of NaOCl and ozone eradicated 99.95 % of the bacteria. Combination of EDTA and ozone reduced E. faecalis up to 91.33 %. The dentin chips showed the following: the highest CFU counts were observed in EDTA group, followed by ozone and NaOCl group. The lowest CFU counts were found in NaOCl-ozone group and EDTA-ozone group.
conclusionsOzone reduced E. faecalis, even organised in a biofilm, however, lower than NaOCl. No treatment reduced totally the bacteria. CLINICAL RELEVANCE: Used as an adjuvant, ozone can increase the efficacy of conventional rinsing like EDTA and presents an alternative treatment when NaOCl cannot be used e.g. in teeth with a wide-open apical foramen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.