Evidence map›Paper›PMID 26637411›Full record

ArticleWorld journal of surgical oncology2015

Is the routine use of a water-soluble contrast enema prior to closure of a loop ileostomy necessary? A review of a single institution experience.

Nikoletta Dimitriou, Sofoklis Panteleimonitis, Ajit Dhillon, Kirsten Boyle, Mike Norwood, David Hemingway, Justin Yeung, Andrew Miller

Open access · goldAbstract read
In one paragraph

Article in World journal of surgical oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Preoperative anastomotic evaluation prior to ileostomy closure: A 5-year UK survey, systematic review, and meta-analysis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Pooled it
  2. Review
  3. Flexible endoscopy is enough diagnostic prior to loop ileostomy reversal.International journal of colorectal disease · 2021
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nikoletta DimitriouColorectal Department, Leicester Royal Infirmary, Leicester, UK. nicdem_gr@hotmail.com.
Sofoklis PanteleimonitisColorectal Department, Leicester Royal Infirmary, Leicester, UK. sofoklis_p@hotmail.com.
Ajit DhillonColorectal Department, Leicester Royal Infirmary, Leicester, UK. ajitdhillon@doctors.org.uk.
Kirsten BoyleColorectal Department, Leicester Royal Infirmary, Leicester, UK. kirsten.boyle@uhl-tr.nhs.uk.
Mike NorwoodColorectal Department, Leicester Royal Infirmary, Leicester, UK. mike.norwood@uhl-tr.nhs.uk.
David HemingwayColorectal Department, Leicester Royal Infirmary, Leicester, UK. david.hemingway@uhl-tr.nhs.uk.
Justin YeungColorectal Department, Leicester Royal Infirmary, Leicester, UK. Justin.Yeung@uhl-tr.nhs.uk.
Andrew MillerColorectal Department, Leicester Royal Infirmary, Leicester, UK. andrew.miller@uhl-tr.nhs.uk.
Leicester Royal Infirmary · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aims of the study were to determine the radiological leak rate in those patients who had undergone a resection for left-sided colorectal cancer and to see if the presence of a leak can be related with the postoperative clinical period. We also aimed to identify any common factors between patients with leak.

methodsA retrospective analysis of prospectively collected data of all patients who underwent a left-sided colorectal cancer resection with formation of a defunctioning ileostomy was undertaken. Between 2005 and 2010, 418 such patients were identified.

resultsA water-soluble contrast enema was performed in 339 patients (81.1 %). Of these, 24 (7.1 %) were reported to show an anastomotic leak. Data for these 24 patients is presented in this study. Twenty-three (95.8 %) of the leaks occurred in patients who had undergone an anterior resection; 95.8 % of the patients with a leak were male. Fifteen (62.5 %) patients underwent neo-adjuvant radiation. The mean length of stay in those patients shown to have a subsequent radiological leak was 18.8 days (median), compared with the overall unit figures of 12 days. Only 29.2 % of the patients who had a leak identified had an uncomplicated postoperative period. Overall 87.5 % of the patients had a reversal of the ileostomy.

conclusionsRadiological leakage is not uncommon. The majority of patients, who were shown to have a radiological leak in this study, were male, had undergone an anterior resection, had received neo-adjuvant radiation, had a longer initial length of stay and had postoperative complications. Water-soluble contrast enemas could be selectively used in patients with these characteristics.

Indexed as

Anastomotic LeakAgedAged, 80 and overAnastomosis, SurgicalContrast MediaEnemaFemaleFollow-Up StudiesHumansIleostomyMaleMiddle AgedNeoplasm StagingPostoperative ComplicationsPrognosisProspective StudiesContrast Media

Identifiers

PMID26637411
PMCPMC4670542
OpenAlexW2182421380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.