Trial reportPloS one2015
Clinical Manifestation of Depression after Stroke: Is It Different from Depression in Other Patient Populations?
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Comparing the Symptomatology of Post-stroke Depression with Depression in the General Population: A Systematic Review.Neuropsychology review · 2024Pooled it
- Prevalence and natural history of depression after stroke: A systematic review and meta-analysis of observational studies.PLoS medicine · 2023Pooled it
- Diagnosis and etiology of poststroke depression: A review.World journal of psychiatry · 2025Review
- Mechanism of Treadmill Exercise Combined with Rich Environmental Stimulation to Improve Depression in Post-stroke Depression Model Rats.Actas espanolas de psiquiatria · 2024Article
- Intravenous thrombolysis and risk of early-onset post-stroke depression: a propensity score matched cohort study.Frontiers in neurology · 2024Article
- Integrative-interpersonal dynamic therapy for poststroke depression (INID): study protocol of a randomised controlled pilot trial.BMJ open · 2023Article
- Predictors of post-stroke depression: Validation of established risk factors and introduction of a dynamic perspective in two longitudinal studies.Frontiers in psychiatry · 2023Article
- The Relationship Between 5-Hydroxytryptamine and Its Metabolite Changes With Post-stroke Depression.Frontiers in psychiatry · 2022Review
- Psychiatric traits and intracerebral hemorrhage: A Mendelian randomization study.Frontiers in psychiatry · 2022Article
- Prevalence and Course of Depression During the First Year After Mild to Moderate Stroke.Journal of the American Heart Association · 2021Article
- Sleep Disorders in Stroke: An Update on Management.Aging and disease · 2021Review
- Depressed Mood after Stroke: Predictive Factors at Six Months Follow-Up.International journal of environmental research and public health · 2020Observational
- An iPad application-based intervention for improving post-stroke depression symptoms in a convalescent rehabilitation ward: A pilot randomized controlled clinical trial protocol.Internet interventions · 2020Article
- Article
- Association Between Anxiety, Depression, and Post-traumatic Stress Disorder and Outcomes After Ischemic Stroke.Frontiers in neurology · 2018Article
- Psychometric evaluation of the Signs of Depression Scale with a revised scoring mechanism in stroke patients with communicative impairment.Clinical rehabilitation · 2017Article
- Implementation and feasibility of the stroke nursing guideline in the care of patients with stroke: a mixed methods study.BMC nursing · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite ample research on depression after stroke, the debate continues regarding whether symptoms such as sleep disturbances, loss of energy, changes in appetite and diminished concentration should be considered to be consequences of stroke or general symptoms of depression. By comparing symptoms in depressed and non-depressed stroke patients with patients in general practice and patients with symptomatic atherosclerotic diseases, we aim to further clarify similarities and distinctions of depression after stroke and depression in other patient populations. Based on this, it is possible to determine if somatic symptoms should be evaluated in stroke patients in diagnosing depression after stroke.
methodsAn observational multicenter study is conducted in three hospitals and seven general practices including 382 stroke patients admitted to hospital with a clinical diagnosis of intracerebral hemorrhage or ischemic infarction, 1160 patients in general practice (PREDICT-NL), and 530 patients with symptomatic atherosclerotic diseases (SMART-Medea).
resultsThe prevalence of major depressive disorder according to DSM-IV criteria was 14.1% (95% CI 11.0%-18.0%) in the stroke cohort, 5.4% (95% CI 3.8%-7.9%) in the symptomatic atherosclerotic diseases cohort and 12.9% (95% CI 11.1%-15.0%) in the general practice cohorts. Comparing depressed patients of the three cohorts demonstrated broadly similar symptom profiles, as well as comparable levels of individual symptom prevalence. However, the stroke patients suffered more severely from these symptoms than patients in the other populations.
conclusionsThe findings suggest that depression after stroke is not a different type of depression. This finding indicates that all depressive symptoms should be evaluated in stroke patients, including somatic symptoms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.