ArticlePloS one2015
Exploring the Antibacterial and Antifungal Potential of Jellyfish-Associated Marine Fungi by Cultivation-Dependent Approaches.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Endophytic Fungi Associated with Seaweeds as Potential Producers of Antimicrobial Compounds.Marine biotechnology (New York, N.Y.) · 2026Article
- Fungal symbionts of marine organisms: The case ofAIMS microbiology · 2026Review
- Discovery of Novel Phenolic Compounds fromInternational journal of molecular sciences · 2025Article
- Chemical Defenses in Medusozoa.Marine drugs · 2025Review
- Isolation of a novel marineJournal of biosciences · 2025Article
- A fungi hotspot deep in the ocean: explaining the presence of Gjaerumia minor in equatorial Pacific bathypelagic waters.Scientific reports · 2024Article
- From marine neglected substrata new fungal taxa of potential biotechnological interest: the case ofFrontiers in microbiology · 2024Article
- Bioactivity Profiling and Untargeted Metabolomics of Microbiota Associated with Mesopelagic JellyfishMarine drugs · 2023Article
- Combination of Solid State and Submerged Fermentation Strategies to Produce a New Jellyfish-Based Food.Foods (Basel, Switzerland) · 2022Article
- Transcriptomic studies on Purpureocillium lilacinum reveal molecular mechanisms of response to fluconazole and itraconazole.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Diversity and Antiaflatoxigenic Activities of Culturable Filamentous Fungi from Deep-Sea Sediments of the South Atlantic Ocean.Mycobiology · 2021Article
- Production and identification of two antifungal terpenoids from the Posidonia oceanica epiphytic Ascomycota Mariannaea humicola IG100.Microbial cell factories · 2020Article
- Identification of Safety and Quality Parameters for Preparation of Jellyfish Based Novel Food Products.Foods (Basel, Switzerland) · 2019Article
- Marine Fungi from the SpongeMarine drugs · 2019Article
- DNA metabarcoding unveils multiscale trophic variation in a widespread coastal opportunist.Molecular ecology · 2019Article
- Diversity ofFrontiers in microbiology · 2019Article
- Production and Identification of Inthomycin B Produced by a Deep-Sea Sediment-Derived Streptomyces sp. YB104 Based on Cultivation-Dependent Approach.Current microbiology · 2018Article
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6 authors.
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Abstract
Fungi isolated from marine invertebrates are of considerable importance as new promising sources of unique secondary metabolites with significant biomedical potential. However, the cultivable fungal community harbored in jellyfish was less investigated. In this work, we seek to recover symbiotic fungi from different tissues of jellyfish Nemopilema nomurai. A total of seven morphotypes were isolated, which were assigned into four genera (Aspergillus, Cladosporium, Purpureocillium, and Tilletiopsis) from two phyla (Ascomycota and Basidiomycota) by comparing the rDNA-ITS sequences with the reference sequences in GenBank. The most fungi were found in the inner tissues of subumbrella. Two of the cultivation-independent procedures, changing media type and co-cultivation, were employed to maximize the complexity of metabolites. Thus, thirteen EtOAc gum were obtained and fingerprinted by High Performance Liquid Chromatography (HPLC) equipped with a photodiode array (PDA) detector. Antibacterial and antifungal activities of these complex mixtures were tested against a panel of bacterial and fungal pathogens. The antimicrobial results showed that all of the 13 EtOAc extracts displayed different levels of antibacterial activity, three of which exhibited strong to significant antibacterial activity to the bacterial pathogens Staphylococcus aureus and Salmonella entrica. Antifungal activity indicated that the EtOAc extracts from pure culture of Aspergillus versicolor and co-culture of A. versicolor and Tilletiopsis sp. in rice media were promising for searching new compounds, with the maximal mycelial growth inhibition of 82.32% ± 0.61% for Rhizoctonia solani and 48.41% ± 11.02% for Botrytis cinerea at 200 μg/ml, respectively. This study is the first report on the antibacterial and antifungal activity of jellyfish-associated fungi and allows the first sight into cultivable fungal community residing in jellyfish. Induced metabolites by cultivation-dependent approaches provides a new reservoir for drug discovery from jellyfish-derived fungi.
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